Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia (Q24322068)

inferred from title

author

Annette Schmitt-Gräff

3

Annette Schmitt-Gräff

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William G Wierda

4

William G Wierda

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Michael J. Keating

5

Michael J Keating

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Jan A Burger

6

Jan A Burger

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Andrea Bürkle

1

Andrea Bürkle

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Matthias Niedermeier

2

The nervous system as ectopic germinal center: CXCL13 and IgG in lyme neuroborreliosis

Matthias Niedermeier

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language of work or name

English

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publication date

1 November 2007

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published in

Blood

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volume

110

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issue

9

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page(s)

3316-25

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cites work

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A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

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BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.

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CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity

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A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1

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Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

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In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment

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In vivo imaging of germinal centres reveals a dynamic open structure

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Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5.

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Role of the microenvironment in chronic lymphocytic leukaemia

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Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjögren's syndrome

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Prediction of Survival in Follicular Lymphoma Based on Molecular Features of Tumor-Infiltrating Immune Cells

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Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia

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B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5

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Developmental switches in chemokine response profiles during B cell differentiation and maturation

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CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

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Signal transduction by CXC chemokine receptor 4. Stromal cell-derived factor 1 stimulates prolonged protein kinase B and extracellular signal-regulated kinase 2 activation in T lymphocytes.

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Aberrant high expression of B lymphocyte chemokine (BLC/CXCL13) by C11b+CD11c+ dendritic cells in murine lupus and preferential chemotaxis of B1 cells towards BLC

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A coordinated change in chemokine responsiveness guides plasma cell movements

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Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection

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Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment

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B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue

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Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma

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BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphoma

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Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis

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7 January 2021

Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha

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CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival

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Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells.

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CXCL13 is an arrest chemokine for B cells in high endothelial venules

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7 January 2021

Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL).

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7 January 2021

The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis

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CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment

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The peritoneal micromilieu commits B cells to home to body cavities and the small intestine

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Distinctive features of "nurselike" cells that differentiate in the context of chronic lymphocytic leukemia

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7 January 2021

Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin lymphomas with widespread nodular dissemination

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7 January 2021

The chemokine CXCL13 (BLC): a putative diagnostic marker for neuroborreliosis

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Lymphoid neogenesis in rheumatoid synovitis

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7 January 2021

Defective B1 cell homing to the peritoneal cavity and preferential recruitment of B1 cells in the target organs in a murine model for systemic lupus erythematosus

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7 January 2021

B-1 B cell development

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7 January 2021