Point mutations in the alpha 2 domain of HLA-A2.1 define a functionally relevant interaction with TAP (Q24323054)

major histocompatibility complex, class I, A

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

TAP binding

1 reference

GOA release 2020-03-11

author name string

J W Lewis

1

0 references

A Neisig

2

0 references

J Neefjes

3

0 references

T Elliott

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

4

0 references

language of work or name

English

0 references

publication date

1 July 1996

0 references

published in

Current Biology

0 references

volume

6

0 references

issue

7

0 references

page(s)

873-83

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Generation, translocation, and presentation of MHC class I-restricted peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Trimming of antigenic peptides in an early secretory compartment

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Peptide-induced conformational change of the class I heavy chain

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Endoplasmic reticulum resident protein of 90 kilodaltons associates with the T- and B-cell antigen receptors and major histocompatibility complex antigens during their assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Interaction of MHC class I molecules with the transporter associated with antigen processing

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Presentation of viral antigen controlled by a gene in the major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

A cluster of mutations in HLA-A2 alpha 2 helix abolishes peptide recognition by T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased ex

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

The membrane-bound and soluble forms of HLA-G bind identical sets of endogenous peptides but differ with respect to TAP association

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Dependence of peptide binding by MHC class I molecules on their interaction with TAP.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

A human-hybridoma system based on a fast-growing mutant of the ARH-77 plasma cell leukemia-derived line

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA-A2 in its recognition by cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021

An improved biochemical method for the analysis of HLA-class I antigens. Definition of new HLA-class I subtypes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900611-5

7 January 2021