DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45 (Q24323084)

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P N Kao

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D W Chan

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L G Lintott

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S P Lees-Miller

Journal of Biological Chemistry

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language of work or name

English

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publication date

23 January 1998

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published in

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volume

273

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issue

4

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page(s)

2136-45

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cites work

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Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

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DNA-dependent protein kinase (Ku protein-p350 complex) assembles on double-stranded DNA.

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p95vav associates with the nuclear protein Ku-70

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Translational control in mammalian cells

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scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase

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HeLa nuclear protein recognizing DNA termini and translocating on DNA forming a regular DNA-multimeric protein complex

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Ku is a general inhibitor of DNA-protein complex formation and transcription

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DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I

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Purification and characterization of the double-stranded DNA-activated protein kinase, DNA-PK, from human placenta

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