Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling (Q24323184)

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English	Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling	scientific article

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20 February 2020

Breast cancer-derived K172N, D301V mutations abolish Na+/H+ exchanger regulatory factor 1 inhibition of platelet-derived growth factor receptor signaling (English)

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Shan Cheng

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20 February 2020

Yang Li

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Ying Yang

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Duiping Feng

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Longyan Yang

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Qian Ma

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Shuai Zheng

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Shuhui Wang

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Songlin Wang

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Junqi He

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5 September 2013

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20 February 2020

Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger

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Regulation of ion transport by the NHERF family of PDZ proteins

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PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling

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Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) is required for the estradiol-dependent increase of phosphatase and tensin homolog (PTEN) protein expression

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NHERF (Na+/H+ exchanger regulatory factor) gene mutations in human breast cancer

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Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity

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The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface

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NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas

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Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1)

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Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells

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EBP50 exerts tumor suppressor activity by promoting cell apoptosis and retarding extracellular signal-regulated kinase activity

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Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling

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Prognostic impact of platelet-derived growth factors in non-small cell lung cancer tumor and stromal cells

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Na+/H+ exchanger regulatory factor 1 expression levels in blood and tissue predict breast tumour clinical behaviour

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10.1016/J.FEBSLET.2013.08.026

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20 February 2020

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