Functions of the alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (Q24324179)

N-acetylglucosamine-1-phosphate transferase subunits alpha and beta

GOA release 2020-03-11

1 reference

carbohydrate phosphorylation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Yi Qian

1

Yi

Qian

1 reference

19 October 2023

Intaek Lee

2

Intaek

Lee

1 reference

19 October 2023

Wang-Sik Lee

3

Wang-Sik

Lee

1 reference

19 October 2023

Meiqian Qian

4

Meiqian

Qian

1 reference

19 October 2023

Mariko Kudo

5

Mariko

Kudo

1 reference

19 October 2023

William M Canfield

6

William M

Canfield

1 reference

19 October 2023

Peter Lobel

7

Peter

Lobel

1 reference

19 October 2023

Stuart Kornfeld

8

Stuart

Journal of Biological Chemistry

Kornfeld

1 reference

19 October 2023

language of work or name

English

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publication date

29 January 2010

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published in

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volume

285

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issue

5

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page(s)

3360-70

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cites work

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Several cooperating binding sites mediate the interaction of a lysosomal enzyme with phosphotransferase

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Murine UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase lacking the gamma-subunit retains substantial activity toward acid hydrolases

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When Mucolipidosis III meets Mucolipidosis II: GNPTA gene mutations in 24 patients

19 March 2017

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Mucolipidosis II is caused by mutations in GNPTA encoding the alpha/beta GlcNAc-1-phosphotransferase

19 March 2017

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Production and characterization of recombinant human CLN2 protein for enzyme-replacement therapy in late infantile neuronal ceroid lipofuscinosis

19 March 2017

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Analysis of the glycosylation and phosphorylation of the alpha-subunit of the lysosomal enzyme, beta-hexosaminidase A, by site-directed mutagenesis

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Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis

19 March 2017

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Lysosomal enzyme phosphorylation. Recognition of a protein-dependent determinant allows specific phosphorylation of oligosaccharides present on lysosomal enzymes

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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TANDEM: matching proteins with tandem mass spectra

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Glucosidase II beta subunit modulates N-glycan trimming in fission yeasts and mammals

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Comparative pathology of murine mucolipidosis types II and IIIC

27 September 2017

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Sorting of lysosomal proteins

27 September 2017

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Proteomics of the lysosome

27 September 2017

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Mice lacking alpha/beta subunits of GlcNAc-1-phosphotransferase exhibit growth retardation, retinal degeneration, and secretory cell lesions

27 September 2017

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The alpha- and beta-subunits of the human UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase [corrected] are encoded by a single cDNA.

27 September 2017

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Recognition of arylsulfatase A and B by the UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-phosphotransferase

27 September 2017

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Molecular basis of variant pseudo-hurler polydystrophy (mucolipidosis IIIC)

27 September 2017

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Human DNase I contains mannose 6-phosphate and binds the cation-independent mannose 6-phosphate receptor

27 September 2017

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A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

27 September 2017

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The role of glycosylation and phosphorylation in the expression of active human beta-glucuronidase

27 September 2017

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A novel mutagenesis strategy identifies distantly spaced amino acid sequences that are required for the phosphorylation of both the oligosaccharides of procathepsin D by N-acetylglucosamine 1-phosphotransferase

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Lysine-based structure in the proregion of procathepsin L is the recognition site for mannose phosphorylation.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Identification of a variant of mucolipidosis III (pseudo-Hurler polydystrophy): a catalytically active N-acetylglucosaminylphosphotransferase that fails to phosphorylate lysosomal enzymes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Lysosomal enzyme phosphorylation in human fibroblasts. Kinetic parameters offer a biochemical rationale for two distinct defects in the uridine diphospho-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Lysine is a common determinant for mannose phosphorylation of lysosomal proteins.

27 September 2017

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The MRH domain suggests a shared ancestry for the mannose 6-phosphate receptors and other N-glycan-recognising proteins

27 September 2017

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The phosphorylation of bovine DNase I Asn-linked oligosaccharides is dependent on specific lysine and arginine residues

30 May 2018

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Biosynthesis of the mannose 6-phosphate recognition marker in transport-impaired mouse lymphoma cells. Demonstration of a two-step phosphorylation.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Analysis of the glycosylation and phosphorylation of the lysosomal enzyme, beta-hexosaminidase B, by site-directed mutagenesis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Phosphorylation of Asn-linked oligosaccharides located at novel sites on the lysosomal enzyme cathepsin D

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823453

Genetic analysis of glucosidase II beta-subunit in trimming of high-mannose-type glycans.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.068650

Colorimetric Method for Determination of Sugars and Related Substances

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.068650

Structural requirements for efficient processing and activation of recombinant human UDP-N-acetylglucosamine:lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.068650

Role of N-linked oligosaccharide flexibility in mannose phosphorylation of lysosomal enzyme cathepsin L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.068650

Identification of the minimal lysosomal enzyme recognition domain in cathepsin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.068650

Lysine-based structure responsible for selective mannose phosphorylation of cathepsin D and cathepsin L defines a common structural motif for lysosomal enzyme targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.068650

Enzyme-based diagnosis of classical late infantile neuronal ceroid lipofuscinosis: comparison of tripeptidyl peptidase I and pepstatin-insensitive protease assays

21 January 2018

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12 December 2020

The phosphorylation of beta-glucuronidase oligosaccharides in mouse P388D1 cells

1 reference

12 December 2020

An assay to detect glycoproteins that contain mannose 6-phosphate

1 reference

12 December 2020

Bovine UDP-N-acetylglucosamine:lysosomal-enzyme N-acetylglucosamine-1-phosphotransferase. I. Purification and subunit structure

1 reference

12 December 2020

The phosphorylation pattern of oligosaccharides in secreted procathepsin D is glycosylation site-specific and independent of the expression of mannose 6-phosphate receptors

1 reference

12 December 2020

Identification of amino acids that modulate mannose phosphorylation of mouse DNase I, a secretory glycoprotein

1 reference

12 December 2020

Proteomics analysis of serum from mutant mice reveals lysosomal proteins selectively transported by each of the two mannose 6-phosphate receptors

1 reference

12 December 2020