The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility (Q24324326)

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English	The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility	scientific article

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scholarly article

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The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility (English)

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SP100 nuclear antigen

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GOA release 2020-03-11

type I interferon signaling pathway

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GOA release 2020-03-11

author name string

T Grötzinger

1

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K Jensen

2

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H Will

3

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language of work or name

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publication date

11 October 1996

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Journal of Biological Chemistry

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271

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41

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25253-60

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Two Nuclear Dot‐Associated Proteins, PML and SplOO, are Often Co‐Autoimmunogenic in Patients with Primary Biliary Cirrhosis

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Two short autoepitopes on the nuclear dot antigen are similar to epitopes encoded by the Epstein-Barr virus

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Nuclear dot antigens may specify transcriptional domains in the nucleus

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A highly amplified mouse gene is homologous to the human interferon-responsive Sp100 gene encoding an autoantigen associated with nuclear dots

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A member of the mouse LRR transcript family with homology to the human Sp100 gene

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Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

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PML, a growth suppressor disrupted in acute promyelocytic leukemia

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PML suppresses oncogenic transformation of NIH/3T3 cells by activated neu.

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Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0).

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Disruption of PML-associated nuclear bodies during human cytomegalovirus infection

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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Interferon response pathways--a paradigm for cytokine signalling?

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Rapid activation by interferon alpha of a latent DNA-binding protein present in the cytoplasm of untreated cells

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Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

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Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either

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Transcription factors induced by interferons alpha and gamma

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Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes

1 reference

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Alpha interferon and gamma interferon stimulate transcription of a single gene through different signal transduction pathways

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Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons

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Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene

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Generation of a variant t(2;8) translocation of Burkitt's lymphoma by site-specific recombination via the kappa light-chain joining signals

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PCR amplification of up to 35-kb DNA with high fidelity and high yield from lambda bacteriophage templates

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Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

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Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element

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Cytokines and growth factors signal through tyrosine phosphorylation of a family of related transcription factors

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A single DNA response element can confer inducibility by both alpha- and gamma-interferons

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Functional differences in the promoters of the interferon-inducible (2'-5')A oligoadenylate synthetase and 6-16 genes in interferon-resistant Daudi cells.

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Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

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based on heuristic

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The "initiator" as a transcription control element

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Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro

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1 reference

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inferred from DOI database lookup

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Identifiers

10.1074/JBC.271.41.25253

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https://api.fatcat.wiki/v0/release/mbtyifwzonapzciyzxvraukaeu

24 November 2022

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