Ro52-mediated monoubiquitination of IKK{beta} down-regulates NF-{kappa}B signalling (Q24324531)

negative regulation of NF-kappaB transcription factor activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Keiji Wada

1

0 references

Motoko Niida

2

0 references

Makoto Tanaka

3

0 references

Tetsu Kamitani

NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1

4

0 references

language of work or name

English

0 references

publication date

December 2009

0 references

published in

Journal of Biochemistry

0 references

volume

146

0 references

issue

6

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page(s)

821-32

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cites work

1 reference

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UnpEL/Usp4 is ubiquitinated by Ro52 and deubiquitinated by itself

19 March 2017

1 reference

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Oncogenic protein UnpEL/Usp4 deubiquitinates Ro52 by its isopeptidase activity

19 March 2017

1 reference

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Autoantigen Ro52 is an E3 ubiquitin ligase

19 March 2017

1 reference

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3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling

19 March 2017

1 reference

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The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1

19 March 2017

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

19 March 2017

1 reference

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

19 March 2017

1 reference

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Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

19 March 2017

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

19 March 2017

1 reference

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Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitination

19 March 2017

1 reference

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NF-kappaB regulation in the immune system

19 March 2017

1 reference

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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

19 March 2017

1 reference

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A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo

19 March 2017

1 reference

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

19 March 2017

1 reference

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Identification of three major sentrinization sites in PML

19 March 2017

1 reference

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Characterization of a second member of the sentrin family of ubiquitin-like proteins

19 March 2017

1 reference

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Human T-cell leukemia virus type I Tax transactivates the promoter of human prointerleukin-1beta gene through association with two transcription factors, nuclear factor-interleukin-6 and Spi-1

19 March 2017

1 reference

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Preferential modification of nuclear proteins by a novel ubiquitin-like molecule

19 March 2017

1 reference

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19 March 2017

Signaling to NF-kappaB

1 reference

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The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

7 April 2017

1 reference

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NF-kappaB: linking inflammation and immunity to cancer development and progression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Does this have a familiar RING?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Ubiquitination of E3 ubiquitin ligase TRIM5 alpha and its potential role

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

HTLV-1 Tax and adult T-cell leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Acetylation of MEK2 and I kappa B kinase (IKK) activation loop residues by YopJ inhibits signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Monoubiquitylation: a recurrent theme in membrane protein transport.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in Yersinia enterocolitica-infected cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Site-specific monoubiquitination of IkappaB kinase IKKbeta regulates its phosphorylation and persistent activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

EH and UIM: endocytosis and more

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Distinct monoubiquitin signals in receptor endocytosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Signal-induced Ubiquitination of IκB Kinase-β

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

When ubiquitin meets ubiquitin receptors: a signalling connection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Function of the Yersinia effector YopJ.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Ubiquitin-like proteins: new wines in new bottles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Ro(SS-A) and anti-Ro(SS-A): an update.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2917061

Activation-induced aggregation and processing of the human Fas antigen. Detection with cytoplasmic domain-specific antibodies

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19675099

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JB/MVP127

0 references

Fatcat ID

release_o7jf7omovrfatexwnu45jgppmu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/o7jf7omovrfatexwnu45jgppmu