Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins (Q24324594)

transcription by RNA polymerase II

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

H Vissing

1

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W K Meyer

2

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L Aagaard

3

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N Tommerup

4

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H J Thiesen

Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

5

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language of work or name

English

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publication date

7 August 1995

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published in

FEBS Letters

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volume

369

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issue

2-3

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page(s)

153-7

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cites work

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An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

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A conserved family of nuclear proteins containing structural elements of the finger protein encoded by Krüppel, a Drosophila segmentation gene.

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The human genome contains hundreds of genes coding for finger proteins of the Krüppel type

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A multigene family encoding several "finger" structures is present and differentially active in mammalian genomes

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The identification and characterization of KRAB-domain-containing zinc finger proteins

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Members of the zinc finger protein gene family sharing a conserved N-terminal module

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Conserved KRAB protein domain identified upstream from the zinc finger region of Kox 8

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A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome

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Repression of transcriptional activity at a distance by the evolutionarily conserved KRAB domain present in a subfamily of zinc finger proteins.

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