Reconstitution, activities, and structure of the eukaryotic RNA exosome (Q24337238)

nuclear exosome (RNase complex)

GO:0000178

1 reference

GO:0000176

exoribonuclease complex

1 reference

cytoplasmic exosome (RNase complex)

GO:1905354

1 reference

nucleolar exosome (RNase complex)

GO:0000177

1 reference

1 reference

Exosome component 10

1 reference

Exosome component 6

1 reference

Exosome component 5

1 reference

Exosome component 1

1 reference

Exosome component 2

1 reference

Exosome component 8

1 reference

Exosome component 3

1 reference

Exosome component 4

1 reference

Exosome component 7

1 reference

exoribonuclease activity

1 reference

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

Christopher D Lima

3

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author name string

Quansheng Liu

series ordinal

1

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Jaclyn C Greimann

series ordinal

2

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language of work or name

English

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publication date

15 December 2006

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published in

Cell

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volume

127

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issue

6

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page(s)

1223-37

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cites work

1 reference

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Degradation of mRNA in eukaryotes

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RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

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Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

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The exosome and the proteasome: nano-compartments for degradation

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An important role for RNase R in mRNA decay

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Structural framework for the mechanism of archaeal exosomes in RNA processing

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Structural basis of 3' end RNA recognition and exoribonucleolytic cleavage by an exosome RNase PH core

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Determining the structure of an unliganded and fully glycosylated SIV gp120 envelope glycoprotein.

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Bringing the role of mRNA decay in the control of gene expression into focus

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SOLVE and RESOLVE: automated structure solution and density modification

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Processing of X-ray diffraction data collected in oscillation mode

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The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases

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AU binding proteins recruit the exosome to degrade ARE-containing mRNAs

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Functional link between the mammalian exosome and mRNA decapping

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A duplicated fold is the structural basis for polynucleotide phosphorylase catalytic activity, processivity, and regulation

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Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

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The archaeal exosome core is a hexameric ring structure with three catalytic subunits

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Subunit architecture of multimeric complexes isolated directly from cells

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An exosome-like complex in Sulfolobus solfataricus

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7 January 2021

A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3'-->5' exoribonuclease activity

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The roles of intersubunit interactions in exosome stability.

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The exosome, a molecular machine for controlled RNA degradation in both nucleus and cytoplasm

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Differential distribution of exosome subunits at the nuclear lamina and in cytoplasmic foci.

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The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

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Functions of the exosome in rRNA, snoRNA and snRNA synthesis

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7 January 2021

A complex prediction: three-dimensional model of the yeast exosome.

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7 January 2021

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Considerations for the refinement of low-resolution crystal structures

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From birth to death: the complex lives of eukaryotic mRNAs

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Structure-based analysis of catalysis and substrate definition in the HIT protein family

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Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs

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A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p

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Eukaryotic mRNA decapping

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Mechanisms of mRNA surveillance in eukaryotes

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Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome

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A new yeast poly(A) polymerase complex involved in RNA quality control

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7 January 2021