Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo (Q24337926)

Splicing factor 3a subunit 2

1 reference

Splicing factor 3a subunit 3

1 reference

Splicing factor 1

1 reference

mRNA 3'-splice site recognition

1 reference

Molecular Biology of the Cell

author name string

Goranka Tanackovic

series ordinal

1

0 references

Angela Krämer

series ordinal

2

0 references

language of work or name

English

0 references

publication date

March 2005

0 references

published in

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volume

16

0 references

issue

3

0 references

page(s)

1366-77

0 references

cites work

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The pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling protein

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A Cajal body-specific pseudouridylation guide RNA is composed of two box H/ACA snoRNA-like domains

19 March 2017

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Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing

19 March 2017

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The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1

19 March 2017

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Domains in human splicing factors SF3a60 and SF3a66 required for binding to SF3a120, assembly of the 17S U2 snRNP, and prespliceosome formation

19 March 2017

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A novel U2 and U11/U12 snRNP protein that associates with the pre-mRNA branch site.

19 March 2017

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A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1

19 March 2017

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Combined biochemical and electron microscopic analyses reveal the architecture of the mammalian U2 snRNP

19 March 2017

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A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site

19 March 2017

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The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription

19 March 2017

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A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition

19 March 2017

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Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A

19 March 2017

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Splicing factor SF3a60 is the mammalian homologue of PRP9 of S.cerevisiae: the conserved zinc finger-like motif is functionally exchangeable in vivo

19 March 2017

1 reference

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Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus

19 March 2017

1 reference

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Mammalian splicing factor SF3a120 represents a new member of the SURP family of proteins and is homologous to the essential splicing factor PRP21p of Saccharomyces cerevisiae.

19 March 2017

1 reference

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Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex

19 March 2017

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Nuclear speckles: a model for nuclear organelles

19 March 2017

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Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP

19 March 2017

1 reference

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Structural basis for recognition of the intron branch site RNA by splicing factor 1

19 March 2017

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Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

19 March 2017

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Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

19 March 2017

1 reference

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Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly

19 March 2017

1 reference

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The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC.

19 March 2017

1 reference

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Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals

19 March 2017

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Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

19 March 2017

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A role for Cajal bodies in the final steps of U2 snRNP biogenesis

19 March 2017

2 references

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19 March 2017

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snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN

24 March 2017

1 reference

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Spliceosomal UsnRNP biogenesis, structure and function

19 March 2017

1 reference

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Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon-intron structure of the gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Human ZFM1 protein is a transcriptional repressor that interacts with the transcription activation domain of stage-specific activator protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway

19 March 2017

1 reference

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Pre-mRNA splicing: awash in a sea of proteins

19 March 2017

1 reference

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Allosteric cascade of spliceosome activation

7 April 2017

1 reference

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Analysis of gene function in somatic mammalian cells using small interfering RNAs

7 April 2017

1 reference

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The structure and function of proteins involved in mammalian pre-mRNA splicing

7 April 2017

1 reference

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Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

7 April 2017

1 reference

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Dilated cardiomyopathy caused by tissue-specific ablation of SC35 in the heart

7 April 2017

1 reference

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Genome-wide RNAi analysis of growth and viability in Drosophila cells

27 September 2017

1 reference

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Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

27 September 2017

1 reference

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The spliceosome: the most complex macromolecular machine in the cell?

27 September 2017

1 reference

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Specificity of short interfering RNA determined through gene expression signatures

27 September 2017

1 reference

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Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

SC35 plays a role in T cell development and alternative splicing of CD45.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins.

27 September 2017

1 reference

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Cajal bodies: the first 100 years

27 September 2017

1 reference

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The question remains: is the spliceosome a ribozyme?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Kinetic role for mammalian SF1/BBP in spliceosome assembly and function after polypyrimidine tract recognition by U2AF.

27 September 2017

1 reference

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A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Functional characterization of SR and SR-related genes in Caenorhabditis elegans

27 September 2017

1 reference

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Splicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viability

27 September 2017

1 reference

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Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20.

27 September 2017

1 reference

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Nuclear bodies: multifaceted subdomains of the interchromatin space.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Nuclear organization of pre-mRNA splicing factors.

27 September 2017

1 reference

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Microinjection of anti-coilin antibodies affects the structure of coiled bodies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Multiple developmental requirements of noisette, the Drosophila homolog of the U2 snRNP-associated polypeptide SP3a60.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Targeting of U2AF65 to sites of active splicing in the nucleus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Three recognition events at the branch-site adenine.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Transfecting mammalian cells: optimization of critical parameters affecting calcium-phosphate precipitate formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Nucleoplasmic organization of small nuclear ribonucleoproteins in cultured human cells.

27 September 2017

1 reference

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Evidence that the 60-kDa protein of 17S U2 small nuclear ribonucleoprotein is immunologically and functionally related to the yeast PRP9 splicing factor and is required for the efficient formation of prespliceosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

In vivo detection of snRNP-rich organelles in the nuclei of mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=551499

A splicing factor that is inactivated during in vivo heat shock is functionally equivalent to the [U4/U6.U5] triple snRNP-specific proteins

27 September 2017

1 reference

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Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy

27 September 2017

1 reference

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Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability

27 September 2017

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U6 snRNA maturation and stability

27 September 2017

1 reference

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Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei

27 September 2017

1 reference

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Mapping of B cell epitopes on small nuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies

30 May 2018

1 reference

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Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies.

30 May 2018

1 reference

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Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

30 May 2018

1 reference

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Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans

30 May 2018

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Presplicing complex formation requires two proteins and U2 snRNP

29 November 2018

1 reference

12 December 2020

Preparation and fractionation of mammalian extracts active in pre-mRNA splicing

1 reference

12 December 2020

Separation of splicing factor SF3 into two components and purification of SF3a activity

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12 December 2020

Interaction of mammalian splicing factor SF3a with U2 snRNP and relation of its 60-kD subunit to yeast PRP9

1 reference

12 December 2020