Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro (Q24337935)

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7 January 2020

title

Double-stranded RNA-dependent protein kinase is required for bone calcification in MC3T3-E1 cells in vitro (English)

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Eukaryotic translation initiation factor 2 alpha kinase 2

7 January 2020

main subject

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protein autophosphorylation

GOA release 2020-03-11

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GOA release 2020-03-11

author

Kaya Yoshida

1

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7 January 2020

author name string

Hirohiko Okamura

2

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7 January 2020

Bruna Rabelo Amorim

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216244%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Akiko Ozaki

4

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7 January 2020

Hiroaki Tanaka

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216244%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Hiroyuki Morimoto

6

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7 January 2020

Tatsuji Haneji

7

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7 January 2020

language of work or name

English

0 references

publication date

7 October 2005

1 reference

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Experimental Cell Research

7 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16216244%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

311

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7 January 2020

issue

1

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7 January 2020

page(s)

117-125

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The double stranded RNA-activated protein kinase induced by interferon: dsRNA-PK.

7 January 2020

cites work

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Role of the double-stranded RNA-activated protein kinase (PKR) in cell regulation

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Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

7 January 2021

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Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase

7 January 2021

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Platelet-derived growth factor signal transduction through the interferon-inducible kinase PKR. Immediate early gene induction

7 January 2021

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Interruption of myogenesis by transforming growth factor beta 1 or EGTA inhibits expression and activity of the myogenic-associated (2'-5') oligoadenylate synthetase and PKR.

7 January 2021

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Tumor-suppressor genes: news about the interferon connection

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An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

7 January 2021

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

7 January 2021

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Cytokines and JAK-STAT signaling

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Turning off signal transducer and activator of transcription (STAT): the negative regulation of STAT signaling

7 January 2021

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Roles and regulation of stat family transcription factors in human breast cancer

7 January 2021

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Stat1 controls postnatal bone formation by regulating fibroblast growth factor signaling in osteoblasts

7 January 2021

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Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation

7 January 2021

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

7 January 2021

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

7 January 2021

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Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways

7 January 2021

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Upregulation of STAT1 protein in cells lacking or expressing mutants of the double-stranded RNA-dependent protein kinase PKR.

7 January 2021

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

7 January 2021

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

7 January 2021

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Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populations

7 January 2021

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In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria

7 January 2021

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Double-stranded RNA-activated protein kinase (PKR) fused to green fluorescent protein induces apoptosis of human embryonic kidney cells: possible role in the Fas signaling pathway.

7 January 2021

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Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2alpha pathway in human osteoblastic MG63 cells.

7 January 2021

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Okadaic acid induces tyrosine phosphorylation of IkappaBalpha that mediated by PKR pathway in human osteoblastic MG63 cells

7 January 2021

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Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

7 January 2021

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Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

7 January 2021

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7 January 2021

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Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations.

7 January 2021

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7 January 2021

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7 January 2021

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Mechanism of interferon action: evidence for intermolecular autophosphorylation and autoactivation of the interferon-induced, RNA-dependent protein kinase PKR

7 January 2021

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7 January 2021

Identifiers

DOI

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7 January 2020

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