TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88 (Q24337940)

positive regulation of interleukin-18-mediated signaling pathway

GOA release 2020-03-11

1 reference

Toll-like receptor adaptor molecule 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Hidehito Tochio

2

0 references

Masahiro Shirakawa

11

object named as

Masahiro Shirakawa

0 references

author name string

Hidenori Ohnishi

1

0 references

Zenichiro Kato

3

0 references

Norio Kawamoto

4

0 references

Takeshi Kimura

5

0 references

Kazuo Kubota

6

0 references

Takahiro Yamamoto

7

0 references

Tatsuyoshi Funasaka

8

0 references

Hiroshi Nakano

9

0 references

Richard W Wong

10

0 references

Naomi Kondo

Creative Commons Attribution 4.0 International

12

0 references

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

0 references

volume

7

0 references

issue

6

0 references

page(s)

e38423

0 references

copyright license

start time

7 June 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Distinct roles of TIR and non-TIR regions in the subcellular localization and signaling properties of MyD88

19 March 2017

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The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

19 March 2017

1 reference

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Binding specificity of Toll-like receptor cytoplasmic domains

19 March 2017

1 reference

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

19 March 2017

1 reference

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The cloning and characterization of human MyD88: a member of an IL-1 receptor related family

19 March 2017

1 reference

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Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

19 March 2017

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Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

19 March 2017

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The structure and binding mode of interleukin-18

19 March 2017

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Pathogen recognition and innate immunity

19 March 2017

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

19 March 2017

1 reference

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19 March 2017

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

19 March 2017

1 reference

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TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling

19 March 2017

1 reference

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The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

19 March 2017

1 reference

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

19 March 2017

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

19 March 2017

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Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

7 April 2017

1 reference

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TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells

27 September 2017

1 reference

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Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

27 September 2017

1 reference

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Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance

27 September 2017

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Signaling to NF-kappaB by Toll-like receptors

27 September 2017

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The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling.

27 September 2017

1 reference

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Role of TLR4 tyrosine phosphorylation in signal transduction and endotoxin tolerance

27 September 2017

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TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.

27 September 2017

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

27 September 2017

1 reference

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Molecular determinants of the myristoyl-electrostatic switch of MARCKS.

27 September 2017

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MyD88 adaptor-like is not essential for TLR2 signaling and inhibits signaling by TLR3.

27 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038423

Structural complementarity of Toll/interleukin-1 receptor domains in Toll-like receptors and the adaptors Mal and MyD88.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038423

Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038423