Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma (Q24338089)

positive regulation of protein kinase B signaling

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Carsten Brock

1

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Michael Schaefer

2

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H Peter Reusch

3

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Cornelia Czupalla

4

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Manuela Michalke

5

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Karsten Spicher

6

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Günter Schultz

7

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Bernd Nürnberg

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

8

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language of work or name

English

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publication date

6 January 2003

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published in

Journal of Cell Biology

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volume

160

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issue

1

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page(s)

89-99

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cites work

1 reference

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Structural basis of 3-phosphoinositide recognition by pleckstrin homology domains

19 March 2017

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The phosphoinositide 3-kinase pathway

19 March 2017

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

19 March 2017

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Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

19 March 2017

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Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical

19 March 2017

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Phoxy lipids: revealing PX domains as phosphoinositide binding modules

19 March 2017

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Synthesis and function of 3-phosphorylated inositol lipids

19 March 2017

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Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

19 March 2017

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Regulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit

19 March 2017

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The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors

19 March 2017

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The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

19 March 2017

1 reference

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19 March 2017

Phosphoinositide kinases

1 reference

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Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits

7 April 2017

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Molecular balance between the regulatory and catalytic subunits of phosphoinositide 3-kinase regulates cell signaling and survival.

27 September 2017

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

27 September 2017

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The role of phosphoinositides in membrane transport

27 September 2017

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Translocation and reversible localization of signaling proteins: a dynamic future for signal transduction

27 September 2017

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Signaling and subcellular targeting by membrane-binding domains

27 September 2017

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How accurately can we image inositol lipids in living cells?

27 September 2017

1 reference

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The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphos

27 September 2017

1 reference

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Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus

27 September 2017

1 reference

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Intracellular movement of green fluorescent protein-tagged phosphatidylinositol 3-kinase in response to growth factor receptor signaling

27 September 2017

1 reference

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Retinoic acid induces selective expression of phosphoinositide 3-kinase gamma in myelomonocytic U937 cells

27 September 2017

1 reference

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Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits

27 September 2017

1 reference

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G proteins endogenously expressed in Sf 9 cells: interactions with mammalian histamine receptors

27 September 2017

1 reference

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

27 September 2017

1 reference

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Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate: a new intracellular signalling system?

27 September 2017

1 reference

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Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha

27 September 2017

1 reference

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A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Recruitment of pleckstrin and phosphoinositide 3-kinase gamma into the cell membranes, and their association with G beta gamma after activation of NK cells with chemokines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

30 May 2018

1 reference

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Purification and characterization of Gbetagamma-responsive phosphoinositide 3-kinases from pig platelet cytosol

30 May 2018

1 reference

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A G protein gamma subunit shares homology with ras proteins.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Anionic phospholipids are involved in membrane targeting of PI 3-kinase gamma

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Gbeta gamma mediate differentiation of vascular smooth muscle cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Gbeta 5gamma 2 is a highly selective activator of phospholipid-dependent enzymes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Structural insights into phosphoinositide 3-kinase catalysis and signalling

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Gbetagamma stimulates phosphoinositide 3-kinase-gamma by direct interaction with two domains of the catalytic p110 subunit.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172741

Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma

29 November 2018

1 reference

12 December 2020

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

1 reference

12 December 2020

Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

1 reference

12 December 2020

Phosphoinositide 3-kinase gamma is a mediator of Gbetagamma-dependent Jun kinase activation

1 reference

12 December 2020

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

12 December 2020

Stimulation of human neutrophils by chemotactic factors is associated with the activation of phosphatidylinositol 3-kinase gamma

1 reference

12 December 2020

Diffusion-limited translocation mechanism of protein kinase C isotypes

1 reference

12 December 2020