BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription (Q24338268)

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28 January 2020

title

BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription (English)

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28 January 2020

1 reference

GOA release 2020-03-11

BCL3 transcription coactivator

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regulation of apoptotic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Timothy W McKeithan

7

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28 January 2020

author name string

Brocke-Heidrich K

1

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28 January 2020

Ge B

2

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28 January 2020

Cvijic H

3

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28 January 2020

Pfeifer G

4

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28 January 2020

Löffler D

5

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28 January 2020

Henze C

6

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28 January 2020

Horn F

8

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28 January 2020

language of work or name

English

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publication date

29 May 2006

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28 January 2020

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28 January 2020

volume

25

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28 January 2020

issue

55

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28 January 2020

page(s)

7297-7304

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The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

28 January 2020

cites work

1 reference

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Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein

21 January 2018

1 reference

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The oncoprotein Bcl-3 directly transactivates through kappa B motifs via association with DNA-binding p50B homodimers

21 January 2018

1 reference

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NF-kappa B-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kappa B1 residence

21 January 2018

1 reference

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Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation

21 January 2018

1 reference

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Diverse effects of BCL3 phosphorylation on its modulation of NF-kappaB p52 homodimer binding to DNA

21 January 2018

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Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma

21 January 2018

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Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells

21 January 2018

1 reference

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Bcl-3 is an interleukin-1-responsive gene in chondrocytes and synovial fibroblasts that activates transcription of the matrix metalloproteinase 1 gene

21 January 2018

1 reference

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The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers

21 January 2018

1 reference

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NF-κB RegulatesBCL3Transcription in T Lymphocytes Through an Intronic Enhancer

21 January 2018

1 reference

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STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis

21 January 2018

1 reference

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Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter

21 January 2018

1 reference

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The proto-oncogene bcl-3 encodes an I kappa B protein

21 January 2018

1 reference

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Oncostatin M and the interleukin-6 and soluble interleukin-6 receptor complex regulate alpha1-antichymotrypsin expression in human cortical astrocytes

21 January 2018

1 reference

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IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages

21 January 2018

1 reference

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High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease

21 January 2018

1 reference

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The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner

21 January 2018

1 reference

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The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control

21 January 2018

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Lymphadenopathy, splenomegaly, and altered immunoglobulin production in BCL3 transgenic mice.

21 January 2018

1 reference

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Bcl-3 expression promotes cell survival following interleukin-4 deprivation and is controlled by AP1 and AP1-like transcription factors

21 January 2018

1 reference

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GSK3-mediated BCL-3 phosphorylation modulates its degradation and its oncogenicity

21 January 2018

1 reference

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Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B

21 January 2018

1 reference

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Stimulus-specific induction of a novel nuclear factor-kappaB regulator, IkappaB-zeta, via Toll/Interleukin-1 receptor is mediated by mRNA stabilization

21 January 2018

1 reference

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Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3

21 January 2018

1 reference

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7 January 2021

The oncoprotein Bcl-3 can facilitate NF-kappa B-mediated transactivation by removing inhibiting p50 homodimers from select kappa B sites.

1 reference

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7 January 2021

Identification of a transcriptional unit adjacent to the breakpoint in the 14;19 translocation of chronic lymphocytic leukemia

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7 January 2021

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

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7 January 2021

Immunological adjuvants promote activated T cell survival via induction of Bcl-3.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209711

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16732314%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 January 2020

1032739870

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017