LAB: a new membrane-associated adaptor molecule in B cell activation (Q24338340)

B cell receptor signaling pathway

GOA release 2020-03-11

1 reference

Linker for activation of T cells family, member 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Erin Janssen

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Minghua Zhu

2

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Weijia Zhang

3

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Surapong Koonpaew

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Weiguo Zhang

Initiation and processing of signals from the B cell antigen receptor

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language of work or name

English

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publication date

February 2003

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published in

Nature Immunology

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volume

4

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issue

2

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page(s)

117-23

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cites work

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The complexity of signaling pathways activated by the BCR.

21 January 2018

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Antigen receptor signaling: integration of protein tyrosine kinase functions.

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Tec family kinases in lymphocyte signaling and function

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Functional dissection of BCR signaling pathways

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Defects in early B-cell development: comparing the consequences of abnormalities in pre-BCR signaling in the human and the mouse

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LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

21 January 2018

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Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

21 January 2018

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Essential role of LAT in T cell development

21 January 2018

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BLNK: a central linker protein in B cell activation

21 January 2018

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SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

21 January 2018

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Requirement for B cell linker protein (BLNK) in B cell development

21 January 2018

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BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

21 January 2018

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An essential role for BLNK in human B cell development

21 January 2018

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LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

21 January 2018

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Divergent human and mouse orthologs of a novel gene (WBSCR15/Wbscr15) reside within the genomic interval commonly deleted in Williams syndrome

21 January 2018

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Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

21 January 2018

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The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

21 January 2018

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RNA interference is mediated by 21- and 22-nucleotide RNAs

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells

21 January 2018

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Lipid rafts and B-cell activation

21 January 2018

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A role for lipid rafts in B cell antigen receptor signaling and antigen targeting

21 January 2018

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CD19 regulates B lymphocyte responses to transmembrane signals

21 January 2018

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Floating the raft hypothesis: lipid rafts play a role in immune cell activation

21 January 2018

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The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19

21 January 2018

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Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha

21 January 2018

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Functional complementation of BLNK by SLP-76 and LAT linker proteins

21 January 2018

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Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.

21 January 2018

1 reference