Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures (Q24338348)

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English	Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures	scientific article

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27 February 2020

Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures (English)

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27 February 2020

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cystic fibrosis

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Sodium channel epithelial 1 subunit gamma

1 reference

GOA release 2020-03-11

BPI fold containing family A member 1

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GOA release 2020-03-11

Sodium channel epithelial 1 subunit beta

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GOA release 2020-03-11

Sodium channel epithelial 1 subunit alpha

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GOA release 2020-03-11

regulation of sodium ion transmembrane transport

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GOA release 2020-03-11

Maxime G. Blanchard

2

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27 February 2020

Stephan Kellenberger

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27 February 2020

Matthew R Redinbo

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Matthew R Redinbo

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27 February 2020

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Carey A Hobbs

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27 February 2020

Omar Alijevic

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27 February 2020

Chong Da Tan

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27 February 2020

Sompop Bencharit

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27 February 2020

Rui Cao

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27 February 2020

Mehmet Kesimer

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27 February 2020

William G Walton

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27 February 2020

Ashley G Henderson

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27 February 2020

M Jackson Stutts

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27 February 2020

Robert Tarran

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11 October 2013

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27 February 2020

American Journal of Physiology - Lung Cellular and Molecular Physiology

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27 February 2020

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27 February 2020

L990-L1001

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27 February 2020

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27 February 2020

SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage

1 reference

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19 March 2017

Differential epithelial expression of the putative innate immune molecule SPLUNC1 in cystic fibrosis

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Flexible peptides and cytoplasmic gels

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The BPI/LBP family of proteins: a structural analysis of conserved regions

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Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways

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Effect of SPLUNC1 protein on the Pseudomonas aeruginosa and Epstein-Barr virus

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Cystic fibrosis

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19 March 2017

Selective regulation of acid-sensing ion channel 1 by serine proteases

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N-linked glycosylation is critical for the plasma membrane localization of nephrin

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Neuropeptide FF and FMRFamide potentiate acid-evoked currents from sensory neurons and proton-gated DEG/ENaC channels

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Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

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Membrane topology of the epithelial sodium channel in intact cells

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Does epithelial sodium channel hyperactivity contribute to cystic fibrosis lung disease?

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27 September 2017

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27 September 2017

PLUNC: a multifunctional surfactant of the airways

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27 September 2017

Primary epithelial cell models for cystic fibrosis research

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27 September 2017

SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice

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27 September 2017

Constraint-based, homology model of the extracellular domain of the epithelial Na+ channel α subunit reveals a mechanism of channel activation by proteases

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27 September 2017

The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airway

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Effect of a temperature increase in the non-noxious range on proton-evoked ASIC and TRPV1 activity

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Allosteric inhibition of the epithelial Na+ channel through peptide binding at peripheral finger and thumb domains

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27 September 2017

SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes

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Dynorphin opioid peptides enhance acid-sensing ion channel 1a activity and acidosis-induced neuronal death

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Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?

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Activation of the epithelial sodium channel (ENaC) by serine proteases

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Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

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The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.

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Maturation of the epithelial Na+ channel involves proteolytic processing of the alpha- and gamma-subunits.

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Restoring airway surface liquid in cystic fibrosis

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12 December 2020

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10.1152/AJPLUNG.00103.2013

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27 February 2020

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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27 February 2020

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Consolidated OpenCitations Corpus – April 2017

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