Nesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarization (Q24338445)

GOA release 2020-03-11

regulation of cell shape

1 reference

GOA release 2020-03-11

1 reference

0 references

Joshua T Morgan

1

0 references

Emily R Pfeiffer

2

0 references

Twanda L Thirkill

3

0 references

Priyadarsini Kumar

4

0 references

Gordon Peng

5

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Heidi N Fridolfsson

6

0 references

Gordon C Douglas

7

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Daniel A Starr

8

0 references

Abdul I Barakat

Molecular Biology of the Cell

9

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language of work or name

English

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publication date

November 2011

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published in

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volume

22

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issue

22

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page(s)

4324-34

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cites work

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Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy

19 March 2017

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Coupling of the nucleus and cytoplasm: role of the LINC complex

19 March 2017

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Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin

19 March 2017

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Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope

19 March 2017

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Syne proteins anchor muscle nuclei at the neuromuscular junction

19 March 2017

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NUANCE, a giant protein connecting the nucleus and actin cytoskeleton

19 March 2017

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Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues

19 March 2017

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Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction

19 March 2017

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Integrins: bidirectional, allosteric signaling machines

19 March 2017

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SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice

19 March 2017

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Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration

19 March 2017

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Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

19 March 2017

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Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture

19 March 2017

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Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation

19 March 2017

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Geometric control of cell life and death

19 March 2017

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Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope.

7 April 2017

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Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope.

27 September 2017

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Keeping the vimentin network under control: cell-matrix adhesion-associated plectin 1f affects cell shape and polarity of fibroblasts

27 September 2017

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Actomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation

27 September 2017

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Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.

27 September 2017

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Modulation of human vascular endothelial cell behaviors by nanotopographic cues

27 September 2017

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Nesprin-1 mutations in human and murine cardiomyopathy

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Nesprin 1 is critical for nuclear positioning and anchorage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

In the middle of it all: mutual mechanical regulation between the nucleus and the cytoskeleton

27 September 2017

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BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome localization

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Bringing KASH under the SUN: the many faces of nucleo-cytoskeletal connections

27 September 2017

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Adhesion signaling - crosstalk between integrins, Src and Rho.

27 September 2017

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A nuclear-envelope bridge positions nuclei and moves chromosomes

27 September 2017

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Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

27 September 2017

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Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Rapid signal transduction in living cells is a unique feature of mechanotransduction.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Requirements for the localization of nesprin-3 at the nuclear envelope and its interaction with plectin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Mechanotransduction from the ECM to the genome: are the pieces now in place?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Mechanotransduction and endothelial cell homeostasis: the wisdom of the cell

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

UNC-83 IS a KASH protein required for nuclear migration and is recruited to the outer nuclear membrane by a physical interaction with the SUN protein UNC-84

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Cell shape provides global control of focal adhesion assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

A model for shear stress sensing and transmission in vascular endothelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Vascular endothelial growth factor C induces angiogenesis in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Impaired flow-induced dilation in mesenteric resistance arteries from mice lacking vimentin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Flow-mediated endothelial mechanotransduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Preferential orientation of centrioles toward the heart in endothelial cells of major blood vessels is reestablished after reversal of a segment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Structural analysis of human neutrophil migration. Centriole, microtubule, and microfilament orientation and function during chemotaxis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Interfering with the connection between the nucleus and the cytoskeleton affects nuclear rotation, mechanotransduction and myogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

The biased lamellipodium development and microtubule organizing center position in vascular endothelial cells migrating under the influence of fluid flow.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Nesprin-3 augments peripheral nuclear localization of intermediate filaments in zebrafish

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Cytoskeletal structure regulates endothelial cell immunogenicity independent of fluid shear stress.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

SU-8 polymer enclosed microchannels with interconnect and nanohole arrays as an optical detection device for biospecies

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Endothelial cell cytoskeletal alignment independent of fluid shear stress on micropatterned surfaces.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Mutations in SYNE1 lead to a newly discovered form of autosomal recessive cerebellar ataxia.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Prestress mediates force propagation into the nucleus

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Vascular endothelial wound closure under shear stress: role of membrane fluidity and flow-sensitive ion channels

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Flow-induced expression of endothelial Na-K-Cl cotransport: dependence on K(+) and Cl(-) channels

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3216658

Shear stress induces spatial reorganization of the endothelial cell cytoskeleton

29 November 2018

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12 December 2020

Shear stress regulates forward and reverse planar cell polarity of vascular endothelium in vivo and in vitro

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12 December 2020

Comparison of the cytoskeleton in aortic endothelial cells in situ and in vitro

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12 December 2020

The effect of fluid shear stress on the migration and proliferation of cultured endothelial cells

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12 December 2020

https://api.crossref.org/works/10.1091%2FMBC.E11-04-0287

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7 January 2021