Viperin inhibits hepatitis C virus replication by interfering with binding of NS5A to host protein hVAP-33 (Q24338873)

negative regulation of viral genome replication

GOA release 2020-03-11

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GOA release 2020-03-11

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Shanshan Wang

1

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Xianfang Wu

2

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Tingting Pan

3

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Wuhui Song

4

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Yaohui Wang

5

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Fei Zhang

6

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Zhenghong Yuan

Journal of General Virology

7

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language of work or name

English

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publication date

January 2012

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published in

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volume

93

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issue

Pt 1

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page(s)

83-92

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cites work

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The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

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Type I interferons in host defense

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Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts

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Yellow fever virus strains Asibi and 17D-204 infect human umbilical cord endothelial cells and induce novel changes in gene expression

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Replication of hepatitis C virus

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Hepatitis C virus non-structural protein NS3 interacts with LMP7, a component of the immunoproteasome, and affects its proteasome activity

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Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication

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The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helix

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Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication

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The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion

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Vesicular stomatitis virus and pseudorabies virus induce a vig1/cig5 homologue in mouse dendritic cells via different pathways.

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Replication of hepatitis C virus RNA occurs in a membrane-bound replication complex containing nonstructural viral proteins and RNA.

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Hepatitis C virus NS5A protein interacts with 2',5'-oligoadenylate synthetase and inhibits antiviral activity of IFN in an IFN sensitivity-determining region-independent manner

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Identification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virus

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Identification and characterization of dominant helper T-cell epitopes in the nucleocapsid protein of severe acute respiratory syndrome coronavirus

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Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

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Interactions between viral nonstructural proteins and host protein hVAP-33 mediate the formation of hepatitis C virus RNA replication complex on lipid raft

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