Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins (Q24522482)

3 July 2017

title

Genetic and biochemical analysis of p23 and ansamycin antibiotics in the function of Hsp90-dependent signaling proteins (English)

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3 July 2017

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S P Bohen

1

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3 July 2017

language of work or name

English

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publication date

1 June 1998

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Molecular and Cellular Biology

3 July 2017

published in

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3 July 2017

volume

18

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3 July 2017

issue

6

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3 July 2017

page(s)

3330-3339

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Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes

3 July 2017

cites work

1 reference

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24 March 2017

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The common 90-kd protein component of non-transformed '8S' steroid receptors is a heat-shock protein

24 March 2017

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Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

24 March 2017

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Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

24 March 2017

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24 March 2017

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

24 March 2017

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In vivo analysis of the Hsp90 cochaperone Sti1 (p60)

24 March 2017

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hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures

24 March 2017

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The translation machinery and 70 kd heat shock protein cooperate in protein synthesis

24 March 2017

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Getting started with yeast

24 March 2017

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24 March 2017

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Improved method for high efficiency transformation of intact yeast cells

24 March 2017

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The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

24 March 2017

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Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events

24 March 2017

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Use and selectivity of herbimycin A as inhibitor of protein-tyrosine kinases

24 March 2017

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Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70.

24 March 2017

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Folding of the glucocorticoid receptor by the reconstituted Hsp90-based chaperone machinery. The initial hsp90.p60.hsp70-dependent step is sufficient for creating the steroid binding conformation

27 September 2017

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Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.

27 September 2017

1 reference

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A role for Hsp90 in retinoid receptor signal transduction

27 September 2017

1 reference

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Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent

27 September 2017

1 reference

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Steroid receptors and their associated proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Reconstitution of retinoid X receptor function and combinatorial regulation of other nuclear hormone receptors in the yeast Saccharomyces cerevisiae

27 September 2017

1 reference

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Isolation of Hsp90 mutants by screening for decreased steroid receptor function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

A role for Hsp90 in cell cycle control: Wee1 tyrosine kinase activity requires interaction with Hsp90.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Hold 'em and fold 'em: chaperones and signal transduction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

LEM1, an ATP-binding-cassette transporter, selectively modulates the biological potency of steroid hormones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Suppression of c-Src Activity by C-Terminal Src Kinase Involves the c-Src SH2 and SH3 Domains: Analysis with Saccharomyces cerevisiae

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Heat-shock protein hsp90 governs the activity of pp60v-src kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Macbecins I and II, new antitumor antibiotics. I. Producing organism, fermentation and antimicrobial activities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Quantitation and intracellular localization of the 85K heat shock protein by using monoclonal and polyclonal antibodies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Steroid receptor regulated transcription of specific genes and gene networks

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

The specific DNA binding activity of the dioxin receptor is modulated by the 90 kd heat shock protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Heterotetrameric structure of the human progesterone receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

A model of glucocorticoid receptor unfolding and stabilization by a heat shock protein complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

An FK506-sensitive transporter selectively decreases intracellular levels and potency of steroid hormones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Proof that hsp70 is required for assembly of the glucocorticoid receptor into a heterocomplex with hsp90.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

The function of steroid hormone receptors is inhibited by the hsp90-specific compound geldanamycin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Mammalian glucocorticoid receptor derivatives enhance transcription in yeast

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Evidence that the 90-kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Reduced levels of hsp90 compromise steroid receptor action in vivo

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Growth inhibition of virus transformed cells in vitro and antitumor activity in vivo of geldanamycin and its derivatives

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Complete DNA sequence of yeast chromosome XI.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Mutations in Hsp83 and cdc37 impair signaling by the sevenless receptor tyrosine kinase in Drosophila.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Hsp90 mutants disrupt glucocorticoid receptor ligand binding and destabilize aporeceptor complexes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Antitumor and cytocidal activities of a newly isolated benzenoid ansamycin, macbecin I

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Interaction of the Rous sarcoma virus protein pp60src with the cellular proteins pp50 and pp90.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=108914

Retinoic acid receptor belongs to a subclass of nuclear receptors that do not form "docking" complexes with hsp90

29 November 2018

1 reference

12 December 2020

Protein components of the nonactivated glucocorticoid receptor

1 reference

12 December 2020

A heat shock protein complex isolated from rabbit reticulocyte lysate can reconstitute a functional glucocorticoid receptor-Hsp90 complex

1 reference

12 December 2020

Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes

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12 December 2020

Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae

1 reference

12 December 2020

A novel chaperone complex for steroid receptors involving heat shock proteins, immunophilins, and p23

1 reference

12 December 2020

Evidence that the 90-kDa phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein

1 reference

12 December 2020

Glucocorticoid receptor mutants that are constitutive activators of transcriptional enhancement

1 reference

12 December 2020

Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways

1 reference

12 December 2020

The 23-kDa Acidic Protein in Reticulocyte Lysate Is the Weakly Bound Component of the hsp Foldosome That Is Required for Assembly of the Glucocorticoid Receptor into a Functional Heterocomplex with hsp90

1 reference

12 December 2020

Binding of p23 and hsp90 during assembly with the progesterone receptor

1 reference

12 December 2020

A cyclophilin function in Hsp90-dependent signal transduction

1 reference

12 December 2020

Functional specificity among Hsp70 molecular chaperones

1 reference

12 December 2020

Nucleotides and two functional states of hsp90

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.18.6.3330

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3 July 2017

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