Hormonal regulation of Gi2 alpha-subunit phosphorylation in intact hepatocytes (Q24527360)

2

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B E Lavan

3

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P J Parker

4

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V J Hruby

5

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G Milligan

6

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M D Houslay

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin

7

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language of work or name

English

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publication date

1 June 1990

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published in

Biochemical Journal

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volume

268

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issue

2

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page(s)

449-57

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cites work

1 reference

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Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit

24 March 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

24 March 2017

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Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium

24 March 2017

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G proteins: transducers of receptor-generated signals

24 March 2017

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Stimulation of phospholipase A2 activity in bovine rod outer segments by the beta gamma subunits of transducin and its inhibition by the alpha subunit

7 April 2017

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Techniques used in the identification and analysis of function of pertussis toxin-sensitive guanine nucleotide binding proteins

27 September 2017

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Strategies for identifying functionally active domains upon cell surface receptors

27 September 2017

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Guanine-nucleotide-binding proteins expressed in rat white adipose tissue. Identification of both mRNAs and proteins corresponding to Gi1, Gi2 and Gi3.

27 September 2017

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Expression of Go alpha mRNA and protein in bovine tissues

27 September 2017

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Influence of cholera toxin on the regulation of adenylate cyclase by GTP

27 September 2017

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The glucagon receptor of rat liver plasma membrane can couple to adenylate cyclase without activating it.

27 September 2017

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Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor

27 September 2017

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Forskolin and ethanol both perturb the structure of liver plasma membranes and activate adenylate cyclase activity.

30 May 2018

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Islet-activating protein blocks glucagon desensitization in intact hepatocytes

30 May 2018

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Krebs EG: Purification and characterization of a protein inhibitor of adenosine 3',5'-monophosphate-dependent protein kinases.

30 May 2018

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Modulation of adenylate cyclase of human platelets by phorbol ester. Impairment of the hormone-sensitive inhibitory pathway

30 May 2018

1 reference

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Insulin inhibits the cholera-toxin-catalysed ribosylation of a Mr-25000 protein in rat liver plasma membranes

30 May 2018

1 reference

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Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase

30 May 2018

1 reference

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The G protein-gated atrial K+ channel is stimulated by three distinct Gi alpha-subunits

30 May 2018

1 reference

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The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go.

30 May 2018

1 reference

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A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets

30 May 2018

1 reference

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Evidence indicating that the glucagon-induced increase in cytoplasmic free Ca2+ concentration in hepatocytes is mediated by an increase in cyclic AMP concentration

30 May 2018

1 reference

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Persistent activation of the alpha subunit of Gs promotes its removal from the plasma membrane

30 May 2018

1 reference

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Glucagon desensitization of adenylate cyclase and stimulation of inositol phospholipid metabolism does not involve the inhibitory guanine nucleotide regulatory protein Gi, which is inactivated upon challenge of hepatocytes with glucagon

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131453

Treatment of intact hepatocytes with either the phorbol ester TPA or glucagon elicits the phosphorylation and functional inactivation of the inhibitory guanine nucleotide regulatory protein Gi.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131453

Direct activation of mammalian atrial muscarinic potassium channels by GTP regulatory protein Gk.

30 May 2018

1 reference

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Diabetes abolishes the GTP-dependent, but not the receptor-dependent inhibitory function of the inhibitory guanine-nucleotide-binding regulatory protein (Gi) on adipocyte adenylate cyclase activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131453

Differential effects of tryptophan on glucose synthesis in rats and guinea pigs

30 May 2018

1 reference

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Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131453

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones.

29 November 2018

1 reference

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Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes

29 November 2018

1 reference

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Activation of two signal-transduction systems in hepatocytes by glucagon

29 November 2018

1 reference

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Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131453

Cholera toxin mediated activation of adenylate cyclase in intact rat hepatocytes

29 November 2018

1 reference

12 December 2020

Glucagon amino groups. Evaluation of modifications leading to antagonism and agonism

1 reference

12 December 2020

Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II

1 reference

12 December 2020

Effects of phosphorylation of inhibitory GTP-binding protein by cyclic AMP-dependent protein kinase on its ADP-ribosylation by pertussis toxin, islet-activating protein

1 reference

12 December 2020

Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles

1 reference

12 December 2020

Thrombin and phorbol esters cause the selective phosphorylation of a G protein other than Gi in human platelets

1 reference

12 December 2020

Heterologous desensitization of the liver adenylyl cyclase: analysis of the role of G-proteins

1 reference

12 December 2020

6 Catalytic subunit of cAMP-dependent protein kinase

1 reference

12 December 2020

Evidence for the role of phosphorylase kinase, protein kinase C, and other Ca2+-sensitive protein kinases in the response of hepatocytes to angiotensin II and vasopressin

1 reference

12 December 2020