RPE65 is the isomerohydrolase in the retinoid visual cycle (Q24530226)

ChEBI release 2020-05-28

Gennadiy Moiseyev

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Ying Chen

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Yusuke Takahashi

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Bill X Wu

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Jian-Xing Ma

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

30 August 2005

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published in

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volume

102

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issue

35

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page(s)

12413-8

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cites work

Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE

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Molecular and biochemical characterization of lecithin retinol acyltransferase

24 March 2017

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Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy

24 March 2017

1 reference

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The structure of a retinal-forming carotenoid oxygenase

24 March 2017

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Rpe65 Is a Retinyl Ester Binding Protein That Presents Insoluble Substrate to the Isomerase in Retinal Pigment Epithelial Cells

24 March 2017

1 reference

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Expression, purification, and MALDI analysis of RPE65

24 March 2017

1 reference

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Mutations in RPE65 cause Leber's congenital amaurosis

24 March 2017

1 reference

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Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

24 March 2017

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Characterization of a plasma retinol-binding protein membrane receptor expressed in the retinal pigment epithelium

24 March 2017

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Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

24 March 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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https://api.crossref.org/works/10.1073/PNAS.0503460102

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https://api.crossref.org/works/10.1073%2FPNAS.0503460102

A palmitoylation switch mechanism in the regulation of the visual cycle

22 April 2017

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Genetic defects in vitamin A metabolism of the retinal pigment epithelium

27 September 2017

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27 September 2017

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Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina

27 September 2017

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Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal

27 September 2017

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Retinal dystrophy of Swedish briard/briard-beagle dogs is due to a 4-bp deletion in RPE65.

27 September 2017

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Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.

27 September 2017

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27 September 2017

How photons start vision

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The retinal pigment epithelial membrane receptor for plasma retinol-binding protein. Isolation and cDNA cloning of the 63-kDa protein.

27 September 2017

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Membrane phospholipids as an energy source in the operation of the visual cycle

27 September 2017

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27 September 2017

1 reference

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RPE65 Operates in the Vertebrate Visual Cycle by Stereospecifically Binding All-trans-Retinyl Esters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1194921

All-trans-retinyl esters are the substrates for isomerization in the vertebrate visual cycle

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1194921

Retinyl esters are the substrate for isomerohydrolase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1194921

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1194921

The rapid intermembraneous transfer of retinoids

29 November 2018

1 reference

12 December 2020

In vivo isomerization of all-trans- to 11-cis-retinoids in the eye occurs at the alcohol oxidation state

1 reference

12 December 2020

Solubilization and partial purification of retinyl ester synthetase and retinoid isomerase from bovine ocular pigment epithelium

1 reference

12 December 2020

Membranes as the energy source in the endergonic transformation of vitamin A to 11-cis-retinol

1 reference

12 December 2020

Control of substrate flow at a branch in the visual cycle

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0503460102

1 reference

ADS bibcode

2005PNAS..10212413M

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1 reference

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PubMed publication ID

16116091

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