Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2. (Q24530532)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032297%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2 (English)

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9 November 2019

1

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9 November 2019

author name string

Ari Tuuttila

series ordinal

2

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9 November 2019

Ulrich Bergmann

series ordinal

3

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9 November 2019

Karl Tryggvason

series ordinal

4

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9 November 2019

language of work or name

English

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publication date

1 May 2002

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Proceedings of the National Academy of Sciences of the United States of America

9 November 2019

published in

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9 November 2019

volume

99

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9 November 2019

issue

11

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9 November 2019

page(s)

7414-7419

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SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages

9 November 2019

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24 March 2017

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24 March 2017

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24 March 2017

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24 March 2017

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24 March 2017

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Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor

24 March 2017

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24 March 2017

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The NMR structure of the inhibited catalytic domain of human stromelysin-1

24 March 2017

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Crystal structure of the haemopexin-like C-terminal domain of gelatinase A

24 March 2017

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24 March 2017

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24 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

24 March 2017

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

24 March 2017

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Domain interactions in the gelatinase A.TIMP-2.MT1-MMP activation complex. The ectodomain of the 44-kDa form of membrane type-1 matrix metalloproteinase does not modulate gelatinase A activation

24 March 2017

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Matrix metalloproteinases

24 March 2017

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Tissue inhibitor of metalloproteinase-2 (TIMP-2) binds to the catalytic domain of the cell surface receptor, membrane type 1-matrix metalloproteinase 1 (MT1-MMP)

24 March 2017

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Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH-terminal domain in a similar manner to TIMP-2

24 March 2017

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The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study

24 March 2017

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Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

24 March 2017

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The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A.

24 March 2017

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27 September 2017

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Identification of the tissue inhibitor of metalloproteinases-2 (TIMP-2) binding site on the hemopexin carboxyl domain of human gelatinase A by site-directed mutagenesis. The hierarchical role in binding TIMP-2 of the unique cationic clusters of hemo

27 September 2017

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Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

30 May 2018

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30 May 2018

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30 May 2018

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30 May 2018

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Binding of tissue inhibitor of metalloproteinases 2 to two distinct sites on human 72-kDa gelatinase. Identification of a stabilization site

30 May 2018

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The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor

30 May 2018

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The C-terminal domain of 72 kDa gelatinase A is not required for catalysis, but is essential for membrane activation and modulates interactions with tissue inhibitors of metalloproteinases

30 May 2018

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Crystal structures of matrilysin-inhibitor complexes

30 May 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Modified Phased Translation Functions and their Application to Molecular-Fragment Location

21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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The hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca2+ for fibronectin and heparin binding. Binding properties of recombinant gelatinase A C domain to extracellular matrix and basement membrane componen

21 January 2018

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Human tissue inhibitor of metalloproteinases 3 interacts with both the N- and C-terminal domains of gelatinases A and B. Regulation by polyanions

21 January 2018

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12 December 2020

Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family

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12 December 2020

Cell surface binding and activation of gelatinase A induced by expression of membrane-type-1-matrix metalloproteinase (MT1-MMP)

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12 December 2020

Kinetic analysis of the binding of human matrix metalloproteinase-2 and -9 to tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2

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12 December 2020

Identifiers

DOI

10.1073/PNAS.102185399

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032297%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

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9 November 2019

PubMed publication ID

12032297

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