Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases. (Q24531388)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12011469%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

Determinants of the cellular specificity of acetaminophen as an inhibitor of prostaglandin H(2) synthases (English)

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8 November 2019

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David Michael Aronoff

series ordinal

2

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8 November 2019

5

John A Oates

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8 November 2019

1

Olivier Boutaud

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8 November 2019

4

Lawrence J Marnett

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8 November 2019

author name string

Jacob H Richardson

series ordinal

3

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8 November 2019

language of work or name

English

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publication date

1 May 2002

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Proceedings of the National Academy of Sciences of the United States of America

8 November 2019

published in

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8 November 2019

volume

99

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8 November 2019

issue

10

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8 November 2019

page(s)

7130-7135

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Cyclooxygenase inhibitors and the antiplatelet effects of aspirin

8 November 2019

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Endothelial cells of the rat brain vasculature express cyclooxygenase-2 mRNA in response to systemic interleukin-1 beta: a possible site of prostaglandin synthesis responsible for fever

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27 September 2017

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Effect of bacterial pyrogen and antipyretics on prostaglandin activity in cerebrospinal fluid of unanaesthetized cats

27 September 2017

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Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

27 September 2017

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27 September 2017

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Pronounced reduction of in vivo prostacyclin synthesis in humans by acetaminophen (paracetamol).

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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30 May 2018

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14 July 2018

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29 November 2018

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29 November 2018

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29 November 2018

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Effect of aspirin, sodium salicylate, and acetaminophen on bleeding

29 November 2018

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12 December 2020

Oxygenation of polyunsaturated fatty acids during prostaglandin biosynthesis by sheep vesicular gland

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12 December 2020

A simple and efficient method for platelet isolation from their plasma

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12 December 2020

The influence of three prostaglandin biosynthesis stimulators on carrageenin-induced edema of rat paw

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12 December 2020

Metabolism of paracetamol to a glutathione conjugate catalyzed by prostaglandin synthetase

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12 December 2020

Comparative analgesic efficacies of aspirin and acetaminophen

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12 December 2020

Peroxidase-mediated formation of reactive metabolites of acetaminophen

1 reference

12 December 2020

Prostaglandin endoperoxide synthetase-dependent cooxidation of acetaminophen to intermediates which covalently bind in vitro to rabbit renal medullary microsomes

1 reference

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Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells

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12 December 2020

Prostaglandin synthetase catalyzed activation of paracetamol

1 reference

12 December 2020

Modification of anti-inflammatory drug effectiveness by ambient lipid peroxides

1 reference

12 December 2020

Leukotriene B4 production by the human alveolar macrophage: a potential mechanism for amplifying inflammation in the lung

1 reference

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Acetaminophen: enzymatic formation of a transient phenoxyl free radical

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Mechanism of the stimulation of prostaglandin H synthase and prostacyclin synthase by the antithrombotic and antimetastatic agent, nafazatrom

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Reduction of prostaglandin H synthase compound II by phenol and hydroquinone, and the effect of indomethacin

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Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2

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The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s)

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Rapid kinetics of tyrosyl radical formation and heme redox state changes in prostaglandin H synthase-1 and -2

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Acetaminophen Inhibits Spinal Prostaglandin E2 Release after Peripheral Noxious Stimulation

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The binding of arachidonic acid in the cyclooxygenase active site of mouse prostaglandin endoperoxide synthase-2 (COX-2). A putative L-shaped binding conformation utilizing the top channel region

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The 1- and 2-electron oxidation of acetaminophen catalyzed by prostaglandin H synthase

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Heme spin states and peroxide-induced radical species in prostaglandin H synthase

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Higher oxidation states of prostaglandin H synthase. EPR study of a transient tyrosyl radical in the enzyme during the peroxidase reaction

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Higher oxidation states of prostaglandin H synthase. Rapid electronic spectroscopy detected two spectral intermediates during the peroxidase reaction with prostaglandin G2

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Acetaminophen and analogs as cosubstrates and inhibitors of prostaglandin H synthase

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Inhibition of human platelet function in vitro and ex vivo by acetaminophen

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12 December 2020

Identifiers

DOI

10.1073/PNAS.102588199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12011469%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

0 references

release_old5iz7ssfdm3buq22b27f5ffy

0 references

OpenCitations bibliographic resource ID

4355824

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12011469%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference