Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia (Q24538611)

6 July 2017

Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia (English)

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6 July 2017

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lymphoblastic leukemia

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5

Stephen P Hunger

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6 July 2017

9

Patricia A Buffler

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6 July 2017

Joseph L Wiemels

1

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6 July 2017

Brian C Leonard

2

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6 July 2017

Yunxia Wang

3

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6 July 2017

Mark R Segal

4

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6 July 2017

Martyn T Smith

6

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6 July 2017

Vonda Crouse

7

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6 July 2017

Xiaomei Ma

8

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6 July 2017

Sharon R Pine

10

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6 July 2017

language of work or name

English

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publication date

1 November 2002

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Proceedings of the National Academy of Sciences of the United States of America

6 July 2017

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6 July 2017

99

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6 July 2017

15101-15106

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6 July 2017

23

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describes a project that uses

6 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC137550/fullTextXML

inferred from PubMed Central ID database lookup

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Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

24 March 2017

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Analysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpoints

24 March 2017

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The diversity of rearranged immunoglobulin heavy chain variable region genes in peripheral blood B cells of preterm infants is restricted by short third complementarity-determining regions but not by limited gene segment usage

24 March 2017

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Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia

21 January 2018

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The role of E2A-PBX1 in leukemogenesis

27 September 2017

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Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells

27 September 2017

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Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

27 September 2017

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Clinical relevance of immunoglobulin mutation analysis

27 September 2017

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E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells

27 September 2017

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27 September 2017

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Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots

27 September 2017

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Cryptic signals and the fidelity of V(D)J joining

27 September 2017

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Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): a report from the Children's Cancer Group.

27 September 2017

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tal-1 deletions in T-cell acute lymphoblastic leukemia as PCR target for detection of minimal residual disease.

27 September 2017

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Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B-CLL progenitor generation

27 September 2017

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Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions.

27 September 2017

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Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

27 September 2017

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Predominance of fetal type DJH joining in young children with B precursor lymphoblastic leukemia as evidence for an in utero transforming event

27 September 2017

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A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. United Kingdom Childhood Cancer Study Investigators

27 September 2017

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Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation

30 May 2018

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Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination

30 May 2018

1 reference

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B precursor acute lymphoblastic leukemia third complementarity-determining regions predominantly represent an unbiased recombination repertoire: leukemic transformation frequently occurs in fetal life.

30 May 2018

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V(D)J recombinase-like activity mediates hprt gene deletion in human fetal T-lymphocytes.

30 May 2018

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In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

30 May 2018

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Presence of N regions in the clonotypic DJ rearrangements of the immunoglobulin heavy-chain genes indicates an exquisitely short latency in t(4;11)-positive infant acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.222481199

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia

21 January 2018

1 reference

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Biased distribution of chromosomal breakpoints involving the MLL gene in infants versus children and adults with t(4;11) ALL.

21 January 2018

1 reference

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Alternative end-joining in follicular lymphomas' t(14;18) translocation.

21 January 2018

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Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion.

21 January 2018

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IgM heavy chain complementarity-determining region 3 diversity is constrained by genetic and somatic mechanisms until two months after birth.

29 November 2018

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Disruption of the multiple tumor suppressor gene MTS1/p16(INK4a)/CDKN2 by illegitimate V(D)J recombinase activity in T-cell acute lymphoblastic leukemias.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=137550

Prenatal origin of acute lymphoblastic leukaemia in children

29 November 2018

1 reference

12 December 2020

Quantitation of leukemia clone-specific antigen gene rearrangements by a single-step PCR and fluorescence-based detection method

1 reference

12 December 2020

The incidence of clonal T-cell receptor rearrangements in B-cell precursor acute lymphoblastic leukemia varies with age and genotype

1 reference

12 December 2020

Microclustering of TEL-AML1 translocation breakpoints in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Templated nucleotide addition and immunoglobulin JH-gene utilization in t(11;14) junctions: implications for the mechanism of translocation and the origin of mantle cell lymphoma

1 reference

12 December 2020

Molecular characterization of genomic AML1-ETO fusions in childhood leukemia

1 reference

12 December 2020

V(D)J recombination: a functional definition of the joining signals

1 reference

12 December 2020

Extensive junctional diversity of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias: implications for the detection of minimal residual disease

1 reference

12 December 2020

Predictability of the t(1;19)(q23;p13) from surface antigen phenotype: implications for screening cases of childhood acute lymphoblastic leukemia for molecular analysis: a Pediatric Oncology Group study

1 reference

12 December 2020

T cell receptor Ddelta2Ddelta3 rearrangement: a suitable allele-specific marker for the detection of minimal residual disease in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

1 reference

12 December 2020

Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual disease

1 reference

12 December 2020

Structure and possible mechanisms of TEL-AML1 gene fusions in childhood acute lymphoblastic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.222481199

1 reference

6 July 2017

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1 reference

6 July 2017

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