The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding (Q24538689)

GOA release 2020-03-11

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Wim G J Hol

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Joseph A. Beavo

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object named as

Joseph A Beavo

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author name string

Sergio E Martinez

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Albert Y Wu

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Natalie A Glavas

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Xiao-Bo Tang

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Stewart Turley

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

1 October 2002

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published in

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volume

99

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issue

20

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page(s)

13260-5

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cites work

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cGMP-stimulated cyclic nucleotide phosphodiesterase regulates the basal calcium current in human atrial myocytes

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Maximum-likelihood density modification

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Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase

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Crystal structure of reovirus attachment protein sigma1 reveals evolutionary relationship to adenovirus fiber

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The GAF domain: an evolutionary link between diverse phototransducing proteins.

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A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway

27 September 2017

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cGMP is tightly bound to bovine retinal rod phosphodiesterase

27 September 2017

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Identification of a noncatalytic cGMP-binding domain conserved in both the cGMP-stimulated and photoreceptor cyclic nucleotide phosphodiesterases

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Substrate and effector specificity of a guanosine 3':5'-monophosphate phosphodiesterase from rat liver

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A stable alpha-helical domain at the N terminus of the RIalpha subunits of cAMP-dependent protein kinase is a novel dimerization/docking motif

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Activation of cGMP-stimulated phosphodiesterase by nitroprusside limits cAMP accumulation in human platelets: effects on platelet aggregation

30 May 2018

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A cyclic GMP-stimulated cyclic nucleotide phosphodiesterase gene is highly expressed in the limbic system of the rat brain

30 May 2018

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Cyclic nucleotide analogs used to study phosphodiesterase catalytic and allosteric sites

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Specificity of cGMP binding to a purified cGMP-stimulated phosphodiesterase from bovine adrenal tissue

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Specific cGMP binding by the cGMP binding domains of cGMP-binding cGMP specific phosphodiesterase

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Identification of key amino acids in a conserved cGMP-binding site of cGMP-binding phosphodiesterases. A putative NKXnD motif for cGMP binding

21 January 2018

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12 December 2020

Specificity of cyclic GMP activation of a multi-substrate cyclic nucleotide phosphodiesterase from rat liver

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12 December 2020

Purification and characterization of a cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from bovine tissues

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12 December 2020

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

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12 December 2020

Purification and characterization of cyclic GMP-stimulated cyclic nucleotide phosphodiesterase from calf liver. Effects of divalent cations on activity

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12 December 2020

High concentrations of a cGMP-stimulated phosphodiesterase mediate ANP-induced decreases in cAMP and steroidogenesis in adrenal glomerulosa cells

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12 December 2020

Structural features of the noncatalytic cGMP binding sites of frog photoreceptor phosphodiesterase using cGMP analogs

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12 December 2020

Purification and partial characterization of membrane-associated type II (cGMP-activatable) cyclic nucleotide phosphodiesterase from rabbit brain

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12 December 2020

The binding of cyclic nucleotide analogs to a purified cyclic GMP-stimulated phosphodiesterase from bovine adrenal tissue

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12 December 2020

Effects of pH on allosteric and catalytic properties of the guanosine cyclic 3',5'-phosphate stimulated cyclic nucleotide phosphodiesterase from calf liver

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12 December 2020

Identifiers

DOI

10.1073/PNAS.192374899

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ADS bibcode

2002PNAS...9913260M

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1 reference

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PubMed publication ID

12271124

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