Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity (Q24539769)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9837816%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity (English)

1 reference

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7 December 2019

1 reference

Peutz-Jeghers syndrome

1 reference

9

1 reference

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7 December 2019

Stilianos Antonarakis

10

1 reference

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7 December 2019

author name string

H Mehenni

1

1 reference

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7 December 2019

C Gehrig

2

1 reference

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7 December 2019

J Nezu

3

1 reference

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7 December 2019

A Oku

4

1 reference

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7 December 2019

M Shimane

5

1 reference

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7 December 2019

C Rossier

6

1 reference

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7 December 2019

N Guex

7

1 reference

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7 December 2019

J L Blouin

8

1 reference

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7 December 2019

language of work or name

English

0 references

publication date

1 December 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9837816%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Human Genetics

7 December 2019

published in

1 reference

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7 December 2019

volume

63

1 reference

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7 December 2019

issue

6

1 reference

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7 December 2019

page(s)

1641-1650

1 reference

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Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

7 December 2019

cites work

1 reference

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Giant protein kinases: domain interactions and structural basis of autoregulation

24 March 2017

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

24 March 2017

1 reference

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

24 March 2017

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A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

24 March 2017

1 reference

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Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

24 March 2017

1 reference

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Landscaping the cancer terrain

24 March 2017

1 reference

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Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

24 March 2017

1 reference

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and hirschsprung disease

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

24 March 2017

1 reference

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Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Splicing of messenger RNA precursors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Peutz-Jeghers disease: most, but not all, families are compatible with linkage to 19p13.3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Peutz-Jeghers syndrome: confirmation of linkage to chromosome 19p13.3 and identification of a potential second locus, on 19q13.4.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Cloning and characterization of a novel serine/threonine protein kinase expressed in early Xenopus embryos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Increased risk of cancer in the Peutz-Jeghers syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Knowledge-based prediction of protein structures and the design of novel molecules

27 September 2017

1 reference

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Cancer and the Peutz-Jeghers syndrome

27 September 2017

1 reference

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

27 September 2017

1 reference

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Ca2+ /S100 regulation of giant protein kinases

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377635

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor

29 November 2018

1 reference

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Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9837816

12 December 2020

inferred from PubMed ID database lookup

Localization of the gene responsible for Peutz-Jeghers syndrome within a 6-cM region of chromosome 19p13.3

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9837816

12 December 2020

inferred from PubMed ID database lookup

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

7 January 2021

Mutations of theRET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumours, and Hirschsprung disease

1 reference

7 January 2021

Generalized Intestinal Polyposis and Melanin Spots of the Oral Mucosa, Lips and Digits

1 reference

7 January 2021

The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

1 reference

7 January 2021

ONCOGENESIS: Landscaping the Cancer Terrain

1 reference

7 January 2021

Identifiers

DOI

10.1086/302159

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9837816%20AND%20SRC:MED&resulttype=core&format=json

release_3d5n75ezvzboljbwihotupiu2i

7 December 2019

Fatcat ID

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9837816%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

PubMed publication ID

9837816

2 references