Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA (Q24544024)

TRNA methyltransferase TYW3 YGL050W

ChEBI release 2020-05-28

ChEBI ID

46574

1 reference

TRNA methyltransferase PPM2 YOL141W

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TRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase YML005W

1 reference

Putative tRNA 4-demethylwyosine synthase YPL207W

1 reference

CYGD: the Comprehensive Yeast Genome Database

2

Yohei Kirino

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author name string

Akiko Noma

series ordinal

1

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Yoshiho Ikeuchi

series ordinal

3

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Tsutomu Suzuki

series ordinal

4

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language of work or name

English

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publication date

17 May 2006

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published in

The EMBO Journal

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volume

25

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issue

10

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page(s)

2142-54

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cites work

1 reference

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Purine bases at position 37 of tRNA stabilize codon-anticodon interaction in the ribosomal A site by stacking and Mg2+-dependent interactions

24 March 2017

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Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

24 March 2017

1 reference

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Carboxyl methylation of the phosphoprotein phosphatase 2A catalytic subunit promotes its functional association with regulatory subunits in vivo

24 March 2017

1 reference

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The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

24 March 2017

1 reference

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Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity

24 March 2017

1 reference

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The proteome of Saccharomyces cerevisiae mitochondria

24 March 2017

1 reference

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Global analysis of protein localization in budding yeast

24 March 2017

1 reference

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A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA.

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs.

24 March 2017

1 reference

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Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria

24 March 2017

1 reference

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A primordial tRNA modification required for the evolution of life?

24 March 2017

1 reference

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S-Adenosylmethionine-dependent methylation in Saccharomyces cerevisiae. Identification of a novel protein arginine methyltransferase

24 March 2017

1 reference

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Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p

24 March 2017

1 reference

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Subcellular localization of the yeast proteome

24 March 2017

1 reference

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Human mitochondrial diseases associated with tRNA wobble modification deficiency

7 April 2017

1 reference

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Specific correlation between the wobble modification deficiency in mutant tRNAs and the clinical features of a human mitochondrial disease

27 September 2017

1 reference

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A unique RNA Fold in the RumA-RNA-cofactor ternary complex contributes to substrate selectivity and enzymatic function

27 September 2017

1 reference

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Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein

27 September 2017

1 reference

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An RNA-modifying enzyme that governs both the codon and amino acid specificities of isoleucine tRNA.

27 September 2017

1 reference

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Wobble modification differences and subcellular localization of tRNAs in Leishmania tarentolae: implication for tRNA sorting mechanism

27 September 2017

1 reference

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Radical mechanisms of S-adenosylmethionine-dependent enzymes

27 September 2017

1 reference

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Adenosylmethionine as a source of 5'-deoxyadenosyl radicals

27 September 2017

1 reference

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The RNA Modification Database: 1999 update

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Changes of post-transcriptional modification of wye base in tumor-specific tRNAPhe

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

The nucleotide sequence of phenylalanine tRNA2of Drosophila melanogaster: four isoacceptors with one basic sequence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Incorporation of lysine into Y base of phenylalanine tRNA in Vero cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Enzymatic conversion of guanosine 3' adjacent to the anticodon of yeast tRNAPhe to N1-methylguanosine and the wye nucleoside: dependence on the anticodon sequence.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Primary structure of Bombyx mori posterior silkgland tRNAPhe

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Origin of the nucleoside Y in yeast tRNAPhe

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Biosynthetic studies of the Y base in yeast phenylalanine tRNA. Incorporation of guanine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

The amino acid sequence of a flavodoxin from the eukaryotic red alga Chondrus crispus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Chromatographic analysis of the aminoacyl-tRNAs which are required for translation of codons at and around the ribosomal frameshift sites of HIV, HTLV-1, and BLV.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Biosynthesis of the nucleoside y in yeast tRNAPhe : Incorporation of the 3-amino-3-carboxypropyl-group from methionine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions

30 May 2018

1 reference

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tRNA actively shuttles between the nucleus and cytosol in yeast

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA.

29 November 2018

1 reference

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Tandem mass spectrometry for structure assignments of wye nucleosides from transfer RNA.

29 November 2018

1 reference

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Structures of two new "minimalist" modified nucleosides from archaeal tRNA.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1462984

Protein phosphatase methyltransferase 1 (Ppm1p) is the sole activity responsible for modification of the major forms of protein phosphatase 2A in yeast

29 November 2018

1 reference

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A Specific Modification Next to the Anticodon of Phenylalanine Transfer Ribonucleic Acid

29 November 2018

1 reference

12 December 2020

Isolation and structure determination of the fluorescent base from bovine liver phenylalanine transfer ribonucleic acid

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12 December 2020

Structure of wye (Yt base) and wyosine (Yt) from Torulopsis utilis phenylalanine transfer ribonucleic acid

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Transfer RNA modification status influences retroviral ribosomal frameshifting

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601105

1 reference

1 reference

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PubMed publication ID

16642040

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