LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes (Q24548189)

2

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S B Joseph

3

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D C Wilpitz

4

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H R Kast

5

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D J Mangelsdorf

6

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P Tontonoz

Proceedings of the National Academy of Sciences of the United States of America

7

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language of work or name

English

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publication date

16 January 2001

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published in

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volume

98

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issue

2

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page(s)

507-12

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cites work

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ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

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The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

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Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

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The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

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Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

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Endogenous apolipoprotein E modulates cholesterol efflux and cholesteryl ester hydrolysis mediated by high-density lipoprotein-3 and lipid-free apolipoproteins in mouse peritoneal macrophages

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12 December 2020

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

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12 December 2020

Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

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12 December 2020

Apolipoprotein E produced by human monocyte-derived macrophages mediates cholesterol efflux that occurs in the absence of added cholesterol acceptors

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12 December 2020

The LXRs: a new class of oxysterol receptors

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12 December 2020

Identifiers

DOI

10.1073/PNAS.98.2.507

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10.1073/PNAS.021488798

1 reference

1279871

ADS bibcode

2001PNAS...98..507L

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1279871

1 reference

1 reference

1 reference