The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage (Q24548305)

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English	The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage	scientific article

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The modified human DNA repair enzyme O(6)-methylguanine-DNA methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation DNA damage (English)

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author name string

A K Teo

1

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H K Oh

2

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R B Ali

3

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B F Li

4

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language of work or name

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publication date

October 2001

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Molecular and Cellular Biology

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21

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20

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7105-14

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The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites

1 reference

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24 March 2017

Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53

1 reference

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24 March 2017

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

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Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

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24 March 2017

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

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The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors

1 reference

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24 March 2017

STATs and gene regulation

1 reference

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7 April 2017

Coactivator and corepressor complexes in nuclear receptor function

1 reference

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7 April 2017

Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 April 2017

Human DNA repair genes

1 reference

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27 September 2017

Repair of O(6)-alkylguanine by alkyltransferases

1 reference

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27 September 2017

Use of HRT and the subsequent risk of cancer.

1 reference

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Molecular epidemiology: recent advances and future directions

1 reference

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Antiestrogens--tamoxifen, SERMs and beyond

1 reference

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27 September 2017

Regulation of p53 downstream genes.

1 reference

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27 September 2017

Histone acetylases and deacetylases in cell proliferation

1 reference

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CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99886

27 September 2017

Implication of localization of human DNA repair enzyme O6-methylguanine-DNA methyltransferase at active transcription sites in transcription-repair coupling of the mutagenic O6-methylguanine lesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99886

27 September 2017

The nuclear targeting and nuclear retention properties of a human DNA repair protein O6-methylguanine-DNA methyltransferase are both required for its nuclear localization: the possible implications

1 reference

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27 September 2017

Insights from the study of animals lacking functional estrogen receptor

1 reference

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Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1 reference

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27 September 2017

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents

1 reference

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DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

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Effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin

1 reference

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30 May 2018

Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a "salt-link".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99886

30 May 2018

Factors influencing the repair of the mutagenic lesion O6-methylguanine in DNA by human O6-methylguanine-DNA methyltransferase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99886

30 May 2018

Induction of resistance to alkylating agents in E. coli: the ada+ gene product serves both as a regulatory protein and as an enzyme for repair of mutagenic damage

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The intracellular signal for induction of resistance to alkylating agents in E. coli

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Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines

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30 May 2018

Molecular mechanism of transcription-repair coupling.

1 reference

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30 May 2018

Estrogen regulation of cell cycle progression in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99886

28 November 2018

Co-activators and co-repressors in the integration of transcriptional responses

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Phenotypic change caused by transcriptional bypass of uracil in nondividing cells

1 reference

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12 December 2020

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Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1 reference

https://pubmed.ncbi.nlm.nih.gov/11564893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The properties of O 6 -methylguanine in templates for RNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11564893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell proliferation kinetics of MCF-7 human mammary carcinoma cells in culture and effects of tamoxifen on exponentially growing and plateau-phase cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11564893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevention of thymic lymphomas in transgenic mice by human O6-alkylguanine-DNA alkyltransferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11564893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A method for simultaneous identification of human active and active-site alkylated O6-methylguanine-DNA methyltransferase and its possible application for monitoring human exposure to alkylating carcinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/11564893

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inferred from PubMed ID database lookup

Growth arrest associated changes of mRNA levels in breast cancer cells measured by semi-quantitative RT-PCR: potential early indicators of treatment response

1 reference

https://pubmed.ncbi.nlm.nih.gov/11564893

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Breast Cancer Prevention Trial shows major benefit, some risk

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based on heuristic

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Identifiers

10.1128/MCB.21.20.7105-7114.2001

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Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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