Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a) (Q24551018)

1

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J Park

2

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H Tran

3

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L S Hu

4

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M E Greenberg

Molecular and Cellular Biology

6

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language of work or name

English

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publication date

February 2001

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published in

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volume

21

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issue

3

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page(s)

952-65

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cites work

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24 March 2017

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Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B

24 March 2017

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Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway

24 March 2017

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Direct control of the Forkhead transcription factor AFX by protein kinase B

24 March 2017

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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

24 March 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

24 March 2017

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Phosphorylation and activation of p70s6k by PDK1

24 March 2017

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Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume

24 March 2017

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

24 March 2017

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90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

24 March 2017

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Roles of phosphorylation sites in regulating activity of the transcription factor Pho4.

24 March 2017

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Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast

24 March 2017

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Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex.

24 March 2017

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

24 March 2017

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14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

24 March 2017

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Unified nomenclature for the winged helix/forkhead transcription factors

24 March 2017

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Regulation of cell death protease caspase-9 by phosphorylation

24 March 2017

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

24 March 2017

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

24 March 2017

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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

24 March 2017

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Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

24 March 2017

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Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

24 March 2017

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Cell cycle and hormonal control of nuclear-cytoplasmic localization of the serum- and glucocorticoid-inducible protein kinase, Sgk, in mammary tumor cells. A novel convergence point of anti-proliferative and proliferative cell signaling pathways

24 March 2017

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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

24 March 2017

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

24 March 2017

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Cellular survival: a play in three Akts

24 March 2017

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

7 April 2017

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

7 April 2017

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

7 April 2017

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Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Forkhead transcription factors: new insights into protein kinase B (c-akt) signaling.

27 September 2017

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Ribosomal S6 kinase 1 (RSK1) activation requires signals dependent on and independent of the MAP kinase ERK.

27 September 2017

1 reference

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Epithelial sodium channel regulated by aldosterone-induced protein sgk.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Mechanisms and consequences of activation of protein kinase B/Akt

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Follicle stimulating hormone-regulated expression of serum/glucocorticoid-inducible kinase in rat ovarian granulosa cells: a functional role for the Sp1 family in promoter activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Negative regulation of the forkhead transcription factor FKHR by Akt.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Differential expression of sgk mRNA, a member of the Ser/Thr protein kinase gene family, in rat brain after CNS injury.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86685

Expression of serum- and glucocorticoid-regulated kinase (sgk) mRNA is up-regulated by GM-CSF and other proinflammatory mediators in human granulocytes

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11154281

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Both isoforms of the cAMP-dependent protein kinase catalytic subunit can activate transcription of the prolactin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11154281

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

h-sgk serine-threonine protein kinase gene as transcriptional target of transforming growth factor beta in human intestine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11154281