Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model (Q24551280)

2

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Christine Pien

3

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Peter J Elliott

4

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Roland Kaufmann

5

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Wolf-Henning Boehncke

Journal of Clinical Investigation

6

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language of work or name

English

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publication date

March 2002

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published in

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volume

109

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issue

5

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page(s)

671-9

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cites work

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Proteasome inhibition: A novel mechanism to combat asthma

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Injection of pre-psoriatic skin with CD4+ T cells induces psoriasis

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27 September 2017

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Dermal injection of immunocytes induces psoriasis

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27 September 2017

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Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production.

27 September 2017

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Characterization of mechanisms involved in transrepression of NF-kappa B by activated glucocorticoid receptors

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Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens?

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Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens

27 September 2017

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Transcriptional regulation of the gene encoding the human C-type lectin leukocyte receptor AIM/CD69 and functional characterization of its tumor necrosis factor-alpha-responsive elements.

27 September 2017

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Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis.

27 September 2017

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A unique phenotype of skin-associated lymphocytes in humans. Preferential expression of the HECA-452 epitope by benign and malignant T cells at cutaneous sites

27 September 2017

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T lymphocytes expressing HECA-452 epitope are present in cutaneous acute graft-versus-host disease and erythema multiforme, but not in acute graft-versus-host disease in gut organs

27 September 2017

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27 September 2017

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Psoriasis and bacterial superantigens--formal or causal correlation?

27 September 2017

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27 September 2017

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27 September 2017

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Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids

27 September 2017

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The superantigen exfoliative toxin induces cutaneous lymphocyte-associated antigen expression in peripheral human T lymphocytes

27 September 2017

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A brain-specific transcription activator

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Selective expression of sialyl-Lewis x and Lewis a epitopes, putative ligands for L-selectin, on peripheral lymph-node high endothelial venules

30 May 2018

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CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry.

30 May 2018

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Evidence for superantigen involvement in skin homing of T cells in atopic dermatitis.

28 November 2018

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New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?

28 November 2018

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Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519

28 November 2018

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12 December 2020

Proteasome inhibition measurements: clinical application

1 reference

12 December 2020

Is psoriasis a T-cell disease?

1 reference

12 December 2020

Antagonistic effects of the staphylococcal enterotoxin a mutant, SEA(F47A/D227A), on psoriasis in the SCID-hu xenogeneic transplantation model

1 reference

12 December 2020

Acute psoriasis associated with Lancefield Group C and Group G cutaneous streptococcal infections

1 reference

12 December 2020

Evidence for the effects of a superantigen in rheumatoid arthritis

1 reference

12 December 2020

A potential role for superantigens in the pathogenesis of psoriasis

1 reference

12 December 2020

Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology

1 reference

12 December 2020

The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression

1 reference

12 December 2020

Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis

1 reference

12 December 2020

Pulling the trigger on psoriasis

1 reference

12 December 2020

Induction of psoriasiform inflammation by a bacterial superantigen in the SCID-hu xenogeneic transplantation model

1 reference

12 December 2020

Superantigens but not mitogens are capable of inducing upregulation of E-selectin ligands on human T lymphocytes

1 reference

12 December 2020

The SCID-hu xenogeneic transplantation model allows screening of anti-psoriatic drugs

1 reference

12 December 2020

1alpha,25-dihydroxycholecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice

1 reference

12 December 2020