Dominant negative murine serum response factor: alternative splicing within the activation domain inhibits transactivation of serum response factor binding targets (Q24554488)

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English	Dominant negative murine serum response factor: alternative splicing within the activation domain inhibits transactivation of serum response factor binding targets	scientific article

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scholarly article

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Dominant negative murine serum response factor: alternative splicing within the activation domain inhibits transactivation of serum response factor binding targets (English)

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alternative mRNA splicing, via spliceosome

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based on heuristic

inferred from title

author name string

N S Belaguli

1

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W Zhou

2

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T H Trinh

3

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M W Majesky

4

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R J Schwartz

5

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language of work or name

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publication date

July 1999

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Molecular and Cellular Biology

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19

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7

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4582-91

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Interaction of ATF6 and serum response factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Interaction with RAP74 subunit of TFIIF is required for transcriptional activation by serum response factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Regulatory role of MEF2D in serum induction of the c-jun promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Structure of serum response factor core bound to DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Serum response factor is essential for mesoderm formation during mouse embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Physical interaction between the mitogen-responsive serum response factor and myogenic basic-helix-loop-helix proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Two independent and interactive DNA-binding subdomains of the Pax6 paired domain are regulated by alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Isolation of two isoforms of the PAX3 gene transcripts and their tissue-specific alternative expression in human adult tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Human SRF-related proteins: DNA-binding properties and potential regulatory targets

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

More is better: Activators and repressors from the same gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

Myocyte enhancer factor (MEF) 2C: a tissue-restricted member of the MEF-2 family of transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

24 March 2017

MADS domain proteins in plant development.

1 reference

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27 September 2017

Organization and myogenic restricted expression of the murine serum response factor gene. A role for autoregulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Growth and differentiation of C2 myogenic cells are dependent on serum response factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Expression and activity of serum response factor is required for expression of the muscle-determining factor MyoD in both dividing and differentiating mouse C2C12 myoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Differential function of Wilms' tumor gene WT1 splice isoforms in transcriptional regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Developmental role of transcription factor isoforms generated by alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Identification of transcriptional activation and inhibitory domains in serum response factor (SRF) by using GAL4-SRF constructs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Expression and purification of the DNA-binding domain of SRF: SRF-DB, a part of a DNA-binding protein which can act as a dominant negative mutant in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Rous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry.

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27 September 2017

A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Serum induction of MEF2/RSRF expression in vascular myocytes is mediated at the level of translation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

The MADS-box family of transcription factors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist

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27 September 2017

Regulation of differentiation of vascular smooth muscle cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Journey to the surface of the cell: Fos regulation and the SRE.

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27 September 2017

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

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27 September 2017

Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Expression of genes encoding the transcription factor SRF during early development of Xenopus laevis: identification of a CArG box-binding activity as SRF.

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27 September 2017

Oct2 transactivation from a remote enhancer position requires a B-cell-restricted activity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

An alternatively spliced Pit-1 isoform altered in its ability to trans-activate

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27 September 2017

Serum response factor p67SRF is expressed and required during myogenic differentiation of both mouse C2 and rat L6 muscle cell lines

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

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27 September 2017

Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

27 September 2017

Developmental switch of CREM function during spermatogenesis: from antagonist to activator

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27 September 2017

Transcripts for functionally distinct isoforms of chicken GATA-5 are differentially expressed from alternative first exons

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30 May 2018

Zebrafish Pax9 encodes two proteins with distinct C-terminal transactivating domains of different potency negatively regulated by adjacent N-terminal sequences

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30 May 2018

Expression of the serum response factor gene is regulated by serum response factor binding sites

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

30 May 2018

The carboxyl-terminal transactivation domain of human serum response factor contains DNA-activated protein kinase phosphorylation sites.

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30 May 2018

Transcriptional repression mediated by the serum response factor.

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30 May 2018

Occupation of the c-fos serum response element in vivo by a multi-protein complex is unaltered by growth factor induction

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30 May 2018

Muscle-specific expression of the cardiac alpha-actin gene requires MyoD1, CArG-box binding factor, and Sp1.

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30 May 2018

Serum response factor affects preinitiation complex formation by TFIID in vitro

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

30 May 2018

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28 November 2018

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Avian serum response factor expression restricted primarily to muscle cell lineages is required for alpha-actin gene transcription.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=84256

28 November 2018

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12 December 2020

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Expression of elastin, smooth muscle alpha-actin, and c-jun as a function of the embryonic lineage of vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10373507

12 December 2020

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A dominant-negative form of transcription factor MEF2 inhibits myogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10373507

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript

1 reference

https://pubmed.ncbi.nlm.nih.gov/10373507

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10373507

12 December 2020

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10.1128/MCB.19.7.4582

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