Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2 (Q24554609)

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R W Ng

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W Y Siu

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A W Lau

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R Y Poon

Molecular and Cellular Biology

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language of work or name

English

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publication date

January 1999

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published in

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volume

19

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issue

1

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page(s)

635-45

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cites work

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

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New functional activities for the p21 family of CDK inhibitors

24 March 2017

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24 March 2017

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24 March 2017

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p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

24 March 2017

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

24 March 2017

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

24 March 2017

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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

24 March 2017

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Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

24 March 2017

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Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression

24 March 2017

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SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

24 March 2017

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The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

24 March 2017

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Identification of functional domains in the neuronal Cdk5 activator protein

24 March 2017

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Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage

24 March 2017

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Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2)

24 March 2017

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Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

24 March 2017

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Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

24 March 2017

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Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase

24 March 2017

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p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

24 March 2017

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Cyclin-dependent kinases: engines, clocks, and microprocessors

24 March 2017

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Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

7 April 2017

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Distinct roles for cyclin-dependent kinases in cell cycle control

7 April 2017

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Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

7 April 2017

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The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.

27 September 2017

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27 September 2017

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Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

27 September 2017

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Inhibition of cyclin-dependent kinases by p21

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921

Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin

27 September 2017

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Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

27 September 2017

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Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits

27 September 2017

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p21-containing cyclin kinases exist in both active and inactive states

27 September 2017

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The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells

27 September 2017

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Cyclin E-CDK2 is a regulator of p27Kip1.

30 May 2018

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Overexpression of cyclin A but not Skp 2 correlates with the tumor relapse of human hepatocellular carcinoma.

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921

Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921

Evidence for a NIMA-like mitotic pathway in vertebrate cells

28 November 2018

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3 Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to immobilon

28 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/9858587