The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis (Q24554649)

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English	The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis	scientific article

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scholarly article

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The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesis (English)

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endoplasmic reticulum

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dehydrodolichyl diphosphate synthase activity

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Gene Ontology release 2020-05-02

Gene Ontology ID

Ditrans,polycis-polyprenyl diphosphate synthase YBR002C

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GOA release 2020-03-11

author name string

M Sato

1

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K Sato

2

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S Nishikawa

3

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A Hirata

4

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J Kato

5

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A Nakano

6

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language of work or name

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publication date

January 1999

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Molecular and Cellular Biology

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19

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1

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471-83

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The biological role of dolichol

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

A simple method for displaying the hydropathic character of a protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

7 April 2017

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Rer1p as common machinery for the endoplasmic reticulum localization of membrane proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Endoplasmic reticulum localization of Sec12p is achieved by two mechanisms: Rer1p-dependent retrieval that requires the transmembrane domain and Rer1p-independent retention that involves the cytoplasmic domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Structural and functional characterization of Sec66p, a new subunit of the polypeptide translocation apparatus in the yeast endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

The CLS2 gene encodes a protein with multiple membrane-spanning domains that is important Ca2+ tolerance in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Nucleotide sequence of AMS1, the structure gene of vacuolar alpha-mannosidase of Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Mutations in yeast calmodulin cause defects in spindle pole body functions and nuclear integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Saccharomyces cerevisiae sec59 cells are deficient in dolichol kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

Yeast/E. coli shuttle vectors with multiple unique restriction sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

24 March 2017

A C-terminal signal prevents secretion of luminal ER proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

7 April 2017

Multiple genes are required for proper insertion of secretory proteins into the endoplasmic reticulum in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

7 April 2017

Yeast Saccharomyces cerevisiae selectable markers in pUC18 polylinkers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

7 April 2017

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

7 April 2017

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

7 April 2017

Molecular cloning, expression, and purification of undecaprenyl diphosphate synthase. No sequence similarity between E- and Z-prenyl diphosphate synthases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RER1 gene product as a component involved in ER localization of Sec12p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Identification of a gene required for membrane protein retention in the early secretory pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Suppression of a sec63 mutation identifies a novel component of the yeast endoplasmic reticulum translocation apparatus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Kex2-dependent invertase secretion as a tool to study the targeting of transmembrane proteins which are involved in ER-->Golgi transport in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Yeast glycosylation mutants are sensitive to aminoglycosides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Yeast secretory mutants that block the formation of active cell surface enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Sorting of soluble ER proteins in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Isolation and deduced amino acid sequence of the gene encoding gp115, a yeast glycophospholipid-anchored protein containing a serine-rich region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Vanadate-resistant yeast mutants are defective in protein glycosylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Structural and functional dissection of a membrane glycoprotein required for vesicle budding from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

27 September 2017

Inhibition of GTP hydrolysis by Sar1p causes accumulation of vesicles that are a functional intermediate of the ER-to-Golgi transport in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

30 May 2018

O-linked oligosaccharides in yeast glycosyl phosphatidylinositol-anchored protein gp115 are clustered in a serine-rich region not essential for its function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

30 May 2018

The GTP-binding Sar1 protein is localized to the early compartment of the yeast secretory pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

30 May 2018

Dolichyl phosphate induces non-bilayer structures, vesicle fusion and transbilayer movement of lipids: a model membrane study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83905

28 November 2018

Biogenesis of vacuolar membrane glycoproteins of yeast Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bilayer membrane destabilization induced by dolichylphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RHO gene products, putative small GTP-binding proteins, are important for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solubilization and characterization of dehydrodolichyl diphosphate synthase from the yeast Saccharomyces carlsbergensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of dolichol in a polyprenol reductase mutant is restored by elevation of cis-prenyl transferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The site of biosynthesis and intracellular deposition of dolichol in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dolichol metabolism in rat liver. Determination of the subcellular distribution of dolichyl phosphate and its site and rate of de novo biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Saccharomyces cerevisiae cis-prenyltransferase required for dolichyl phosphate biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of dolichyl phosphate on permeability and stability of bilayer lipid membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A colony procedure for transformation of Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/9858571

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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