OPA1 requires mitofusin 1 to promote mitochondrial fusion (Q24560014)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509649%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

OPA1 requires mitofusin 1 to promote mitochondrial fusion (English)

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4 January 2020

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4

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4 January 2020

author name string

Sara Cipolat

series ordinal

1

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4 January 2020

Olga Martins de Brito

series ordinal

2

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4 January 2020

Barbara Dal Zilio

series ordinal

3

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4 January 2020

language of work or name

English

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publication date

27 October 2004

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

4 January 2020

published in

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4 January 2020

volume

101

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4 January 2020

issue

45

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4 January 2020

page(s)

15927-15932

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Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

4 January 2020

cites work

1 reference

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Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

24 March 2017

1 reference

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Differential sublocalization of the dynamin-related protein OPA1 isoforms in mitochondria

24 March 2017

1 reference

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Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins.

24 March 2017

1 reference

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Primary structure of a dynamin-related mouse mitochondrial GTPase and its distribution in brain, subcellular localization, and effect on mitochondrial morphology

24 March 2017

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24 March 2017

1 reference

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Control of mitochondrial morphology by a human mitofusin

24 March 2017

1 reference

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

24 March 2017

1 reference

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Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane

24 March 2017

1 reference

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The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion

24 March 2017

1 reference

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UGO1 encodes an outer membrane protein required for mitochondrial fusion

24 March 2017

1 reference

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Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p

24 March 2017

1 reference

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24 March 2017

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24 March 2017

1 reference

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Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Fzo1p is a mitochondrial outer membrane protein essential for the biogenesis of functional mitochondria in Saccharomyces cerevisiae

24 March 2017

1 reference

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hFis1, a novel component of the mammalian mitochondrial fission machinery

24 March 2017

1 reference

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The human dynamin-related protein OPA1 is anchored to the mitochondrial inner membrane facing the inter-membrane space

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Mutation spectrum and splicing variants in the OPA1 gene

24 March 2017

1 reference

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Propagation of the apoptotic signal by mitochondrial waves

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

24 March 2017

1 reference

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Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

24 March 2017

1 reference

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Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

The expanding role of mitochondria in apoptosis

24 March 2017

1 reference

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Coiled coils: new structures and new functions

24 March 2017

1 reference

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A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

7 April 2017

1 reference

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The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

7 April 2017

1 reference

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C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane

7 April 2017

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Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape

7 April 2017

1 reference

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The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fission

7 April 2017

1 reference

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Mitochondrial dynamics and division in budding yeast

27 September 2017

1 reference

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Mitochondria are morphologically and functionally heterogeneous within cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

OPA1 (Kjer type) dominant optic atrophy: a novel mitochondrial disease.

27 September 2017

1 reference

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Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications.

27 September 2017

1 reference

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The many shapes of mitochondrial membranes

27 September 2017

1 reference

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Divide and multiply: organelle partitioning in yeast

27 September 2017

1 reference

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The internal structure of mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Coupling membranes as energy-transmitting cables. I. Filamentous mitochondria in fibroblasts and mitochondrial clusters in cardiomyocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Cytochrome c as an electron shuttle between the outer and inner mitochondrial membranes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

Loss of the intermembrane space protein Mgm1/OPA1 induces swelling and localized constrictions along the lengths of mitochondria

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=528769

28 November 2018

Identifiers

DOI

10.1073/PNAS.0407043101

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509649%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

ADS bibcode

2004PNAS..10115927C

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15509649%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

15509649

2 references