Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1 (Q24561919)

1

0 references

N Hayashi

2

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Y Azuma

3

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T Seki

4

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M Nakamura

5

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N Nakashima

6

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M Yanagida

7

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X He

8

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U Mueller

9

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S Sazer

10

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T Nishimoto

Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis

11

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language of work or name

English

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publication date

15 October 1996

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published in

The EMBO Journal

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volume

15

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issue

20

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page(s)

5595-605

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cites work

1 reference

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RanGAP1 induces GTPase activity of nuclear Ras-related Ran

24 March 2017

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Co-activation of RanGTPase and inhibition of GTP dissociation by Ran-GTP binding protein RanBP1

24 March 2017

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RanBP1, a Ras-like nuclear G protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4

24 March 2017

1 reference

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A giant nucleopore protein that binds Ran/TC4

24 March 2017

1 reference

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The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA

24 March 2017

1 reference

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Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line

24 March 2017

1 reference

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Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide

24 March 2017

1 reference

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Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

24 March 2017

1 reference

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A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

24 March 2017

1 reference

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nup1 mutants exhibit pleiotropic defects in nuclear pore complex function

24 March 2017

1 reference

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Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A family of Ran binding proteins that includes nucleoporins

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Mutants in a yeast Ran binding protein are defective in nuclear transport

24 March 2017

1 reference

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Characterization of a Dominant, Constitutive Mutation, PHOO , for the Repressible Acid Phosphatase Synthesis in Saccharomyces cerevisiae

24 March 2017

1 reference

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Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants

24 March 2017

1 reference

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The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

The SIT4 protein phosphatase functions in late G1 for progression into S phase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

RCC1 in the cell cycle: the regulator of chromosome condensation takes on new roles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Isolation and characterization of the fission yeast protein phosphatase gene ppe1+ involved in cell shape control and mitosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A fission yeast RCC1-related protein is required for the mitosis to interphase transition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A mutant form of the Ran/TC4 protein disrupts nuclear function in Xenopus laevis egg extracts by inhibiting the RCC1 protein, a regulator of chromosome condensation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Nuclear PRP20 protein is required for mRNA export

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Chromosome engineering in Saccharomyces cerevisiae by using a site-specific recombination system of a yeast plasmid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

The fission yeast dis3+ gene encodes a 110-kDa essential protein implicated in mitotic control

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

The Saccharomyces cerevisiae SRK1 gene, a suppressor of bcy1 and ins1, may be involved in protein phosphatase function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

RCC1, a regulator of mitosis, is essential for DNA replication

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Chromosome condensation caused by loss of RCC1 function requires the cdc25C protein that is located in the cytoplasm

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Conserved histidine residues of RCC1 are essential for nucleotide exchange on Ran.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Premature chromatin condensation induced by loss of RCC1 is inhibited by GTP- and GTPgammaS-Ran, but not GDP-Ran

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A murine homolog of the yeast RNA1 gene is required for postimplantation development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Structure of the yeast HIS5 gene responsive to general control of amino acid biosynthesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Premature of chromosome condensation in a ts DNA- mutant of BHK cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

Identification of cut8+ and cek1+, a novel protein kinase gene, which complement a fission yeast mutation that blocks anaphase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

SCM2, a tryptophan permease in Saccharomyces cerevisiae, is important for cell growth

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A yeast mutant, PRP20, altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=452304

A family of proteins that stabilize the Ran/TC4 GTPase in its GTP-bound conformation

28 November 2018

1 reference

12 December 2020

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

1 reference

12 December 2020

Regulation of Cdc2/cyclin B activation by Ran, a Ras-related GTPase

1 reference

12 December 2020

The Kinetic Mechanism of Ran-Nucleotide Exchange Catalyzed by RCC1

1 reference

12 December 2020