Zinc finger-mediated protein interactions modulate Ikaros activity, a molecular control of lymphocyte development (Q24561965)

2

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K Georgopoulos

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L. Sun

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A. Liu

2

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K. Georgopoulos

The Ikaros gene encodes a family of lymphocyte-restricted zinc finger DNA binding proteins, highly conserved in human and mouse

3

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language of work or name

English

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publication date

1 October 1996

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October 1996

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published in

The EMBO Journal

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volume

15

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issue

19

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page(s)

5358-69

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5358-5369

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cites work

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The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene

24 March 2017

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EBF contains a novel zinc coordination motif and multiple dimerization and transcriptional activation domains

24 March 2017

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Three-dimensional solution structure of a single zinc finger DNA-binding domain

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24 March 2017

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Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins

24 March 2017

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A novel genetic system to detect protein-protein interactions

24 March 2017

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The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins

24 March 2017

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Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

24 March 2017

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TBP, a universal eukaryotic transcription factor?

24 March 2017

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The Ikaros gene is required for the development of all lymphoid lineages

24 March 2017

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Transcriptional activation: a complex puzzle with few easy pieces

24 March 2017

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A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

7 April 2017

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Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements

7 April 2017

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Self-association of the erythroid transcription factor GATA-1 mediated by its zinc finger domains

27 September 2017

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Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

27 September 2017

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Molecular detection of deletions involving band q14 of chromosome 13 in retinoblastomas

27 September 2017

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DNA looping and Sp1 multimer links: a mechanism for transcriptional synergism and enhancement

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Structural evidence for the authenticity of the human retinoblastoma gene

27 September 2017

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27 September 2017

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30 May 2018

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30 May 2018

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30 May 2018

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Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism

30 May 2018

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DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1

30 May 2018

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30 May 2018

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Dimerization and the control of transcription by Krüppel.

30 May 2018

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Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8895580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/8895580

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8895580