Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells (Q24562099)

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English	Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells	scientific article

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scholarly article

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Pyridinyl imidazole inhibitors of p38 MAP kinase impair viral entry and reduce cytokine induction by Zaire ebolavirus in human dendritic cells (English)

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Orthoebolavirus zairense

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Zaire ebolavirus

object named as

Zaire ebolavirus

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Joshua C Johnson

object named as

Joshua C Johnson

1

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object named as

Anna N Honko

3

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object named as

Gene G Olinger

5

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Christopher F Basler

object named as

Christopher F Basler

6

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4

object named as

Lisa E Hensley

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author name string

Osvaldo Martinez

2

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language of work or name

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publication date

July 2014

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Antiviral Research

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107

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102-9

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The Tyro3 receptor kinase Axl enhances macropinocytosis of Zaire ebolavirus

1 reference

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24 March 2017

Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

Cellular entry of ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

Serum-induced monocyte differentiation and monocyte chemotaxis are regulated by the p38 MAP kinase signal transduction pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

24 March 2017

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

7 April 2017

Ebola virus exploits a monocyte differentiation program to promote its entry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species- and cell-type-specific manner.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Stress-activated protein kinases are involved in porcine reproductive and respiratory syndrome virus infection and modulate virus-induced cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

The role of antigen-presenting cells in filoviral hemorrhagic fever: gaps in current knowledge

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

New Insights into the p38γ and p38δ MAPK Pathways

1 reference

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27 September 2017

MIF synergizes with Trypanosoma cruzi antigens to promote efficient dendritic cell maturation and IL-12 production via p38 MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Ebola virus enters host cells by macropinocytosis and clathrin-mediated endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway

1 reference

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27 September 2017

Cell entry of avian reovirus follows a caveolin-1-mediated and dynamin-2-dependent endocytic pathway that requires activation of p38 mitogen-activated protein kinase (MAPK) and Src signaling pathways as well as microtubules and small GTPase Rab5 pro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Identification of novel cellular targets for therapeutic intervention against Ebola virus infection by siRNA screening

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27 September 2017

Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Zaire Ebola virus entry into human dendritic cells is insensitive to cathepsin L inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

The p38alpha kinase plays a central role in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

JNK and p38 mitogen-activated protein kinase pathways contribute to porcine circovirus type 2 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Cell adhesion promotes Ebola virus envelope glycoprotein-mediated binding and infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

MAPK signaling contributes to rotaviral-induced cholangiocyte injury and viral replication

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Ebola virus-like particle-induced activation of NF-kappaB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain.

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27 September 2017

The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Modulation of Kaposi's sarcoma-associated herpesvirus infection and replication by MEK/ERK, JNK, and p38 multiple mitogen-activated protein kinase pathways during primary infection

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27 September 2017

Ebola virus: unravelling pathogenesis to combat a deadly disease

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27 September 2017

The biology of p38 kinase: a central role in inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4103912

27 September 2017

Ebola virus: the role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever

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27 September 2017

Generation of eGFP expressing recombinant Zaire ebolavirus for analysis of early pathogenesis events and high-throughput antiviral drug screening

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27 September 2017

HIV-1-induced migration of monocyte-derived dendritic cells is associated with differential activation of MAPK pathways.

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27 September 2017

Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection

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27 September 2017

Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation

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27 September 2017

Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection

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27 September 2017

p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases

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27 September 2017

Effect of p38 Mitogen-Activated Protein Kinase on the Replication of Encephalomyocarditis Virus

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27 September 2017

Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses

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27 September 2017

Influenza-virus-induced signaling cascades: targets for antiviral therapy?

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Inflammatory responses in Ebola virus-infected patients.

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27 September 2017

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27 September 2017

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27 September 2017

p38 mitogen-activated protein kinase inhibitors--mechanisms and therapeutic potentials

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27 September 2017

Filoviral haemorrhagic fevers

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27 September 2017

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27 September 2017

Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase

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27 September 2017

Dual stimulation of MyD88-dependent Toll-like receptors induces synergistically enhanced production of inflammatory cytokines in murine bone marrow-derived dendritic cells.

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28 November 2018

AMP-activated protein kinase facilitates avian reovirus to induce mitogen-activated protein kinase (MAPK) p38 and MAPK kinase 3/6 signalling that is beneficial for virus replication

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28 November 2018

Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-kappaB signaling pathway.

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28 November 2018

Suppression of p38 mitogen-activated protein kinase inhibits hepatitis B virus replication in human hepatoma cell: the antiviral role of nitric oxide

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28 November 2018

Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells.

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28 November 2018

Inhibition of monocyte IL-1 production by the anti-inflammatory compound, SK&F 86002

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12 December 2020

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Antiinflammatory activity of 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles. Isomeric 4-pyridyl and 4-substituted phenyl derivatives

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https://pubmed.ncbi.nlm.nih.gov/24815087

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1016/J.ANTIVIRAL.2014.04.014

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