LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1 (Q24562777)

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C D Jones

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J E Audia

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S Andersson

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L McQuaid

5

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N B Stamm

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B L Neubauer

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P Pennington

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R E Toomey

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D W Russell

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

1 June 1993

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published in

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volume

90

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issue

11

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page(s)

5277-81

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cites work

Structural and biochemical properties of cloned and expressed human and rat steroid 5 alpha-reductases

1 reference

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Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

24 March 2017

1 reference

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Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase

24 March 2017

1 reference

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Expression cloning and regulation of steroid 5 alpha-reductase, an enzyme essential for male sexual differentiation

24 March 2017

1 reference

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Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to finasteride, a competitive inhibitor

24 March 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

24 March 2017

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Regulation of Human Hair Growth by Steroid Hormones. I. Testosterone Metabolism in Isolated Hairs

7 April 2017

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Mutational analysis of the ligand binding domain of the low density lipoprotein receptor

27 September 2017

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Inhibitors of steroid 5 alpha-reductase in benign prostatic hyperplasia, male pattern baldness and acne

27 September 2017

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Benign prostatic hyperplasia. Universal problem among aging men.

27 September 2017

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Endocrine treatment of benign prostatichypertrophy: Current concepts

27 September 2017

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The clinical development of a 5α-reductase inhibitor, finasteride

27 September 2017

1 reference

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Benign prostatic hyperplasia and its treatment

27 September 2017

1 reference

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Steroid 5alpha-reductase in cultured human fibroblasts. Biochemical and genetic evidence for two distinct enzyme activities

27 September 2017

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Tyrosine protein kinase activity of human hyperplastic prostate and carcinoma cell lines PC3 and DU145.

27 September 2017

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The partial dependency of human prostatic growth factor on steroid hormones in stimulating thymidine incorporation into DNA.

30 May 2018

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Characterization of 5 alpha-reductase in cultured human dermal papilla cells from beard and occipital scalp hair

30 May 2018

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Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque

30 May 2018

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A reagent for the non-destructive location of steroids and some other lipophilic materials on silica gel thin-layer chromatograms

30 May 2018

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12 December 2020

5α-Reductase activity in stroma and epithelium of rat prostate and epididymis. A contribution to elucidation of the mechanism for development of hyperplastic growth of prostatic tissue

1 reference

12 December 2020

12. Androgens: Pharmacodynamics and antagonists. Biochemical and biological studies with 4-aza-steroidal 5 alpha-reductase inhibitors

1 reference

12 December 2020

Species differences in prostatic steroid 5 alpha-reductases of rat, dog, and human

1 reference

12 December 2020

The effects of N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamide, a 5 alpha-reductase inhibitor and antiandrogen, on the development of baldness in the stumptail macaque

1 reference

12 December 2020

Identification of a cellular receptor for transforming growth factor-beta in rat ventral prostate and its negative regulation by androgens

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.90.11.5277

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4819246

ADS bibcode

1993PNAS...90.5277H

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4819246

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