Translational regulation by the interferon-induced double-stranded-RNA-activated 68-kDa protein kinase (Q24562903)

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M Wambach

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M L Wong

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A G Hinnebusch

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M G Katze

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

15 May 1993

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published in

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volume

90

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issue

10

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page(s)

4621-5

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cites work

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Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

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Translational control in mammalian cells

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Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

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Mechanism of interferon action: identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2 alpha protein kinase

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Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

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Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNA

27 September 2017

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Metabolism and Expression of RNA Polymerase II Transcripts in Influenza Virus-Infected Cells

27 September 2017

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Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cells

27 September 2017

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Adenovirus VAI RNA complexes with the 68 000 Mr protein kinase to regulate its autophosphorylation and activity

27 September 2017

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Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase

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The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

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The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.

27 September 2017

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The double stranded RNA-activated protein kinase induced by interferon: dsRNA-PK.

27 September 2017

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Gene induction by interferons and double-stranded RNA: selective inhibition by 2-aminopurine

27 September 2017

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Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cells

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Adenovirus virus-associated RNA and translation control

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Functional expression and RNA binding analysis of the interferon-induced, double-stranded RNA-activated, 68,000-Mr protein kinase in a cell-free system

27 September 2017

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Interferon-induced and double-stranded RNA-activated enzymes: a specific protein kinase and 2',5'-oligoadenylate synthetases

27 September 2017

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Antiviral actions of interferon interferon-regulated cellular proteins and their surprisingly selective antiviral activities

27 September 2017

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The integrity of the stem structure of human immunodeficiency virus type 1 Tat-responsive sequence of RNA is required for interaction with the interferon-induced 68,000-Mr protein kinase

27 September 2017

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Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

27 September 2017

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Partial characterization of a cellular factor that regulates the double-stranded RNA-dependent eIF-2 alpha kinase in 3T3-F442A fibroblasts

27 September 2017

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The war against the interferon-induced dsRNA-activated protein kinase: can viruses win?

27 September 2017

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Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

27 September 2017

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The interferon system. A bird's eye view of its biochemistry

27 September 2017

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Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2

27 September 2017

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Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells

27 September 2017

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27 September 2017

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Nuclear-cytoplasmic transport and VAI RNA-independent translation of influenza viral messenger RNAs in late adenovirus-infected cells

30 May 2018

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Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA.

30 May 2018

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Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism

30 May 2018

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Translational control by influenza virus. Selective and cap-dependent translation of viral mRNAs in infected cells

30 May 2018

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CD3-zeta surface expression is required for CD4-p56lck-mediated upregulation of T cell antigen receptor-CD3 signaling in T cells

30 May 2018

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Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase

30 May 2018

1 reference

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Cytosolic double-stranded RNA-dependent protein kinase is likely a dimer of partially phosphorylated Mr = 66,000 subunits

30 May 2018

1 reference

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Detection of protein kinase homologues and viral RNA-binding domains utilizing polyclonal antiserum prepared against a baculovirus-expressed ds RNA-activated 68,000-Da protein kinase

30 May 2018

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Rapid decrease in the levels of the double-stranded RNA-dependent protein kinase during virus infections

30 May 2018

1 reference

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Mechanism of interferon action. Activation of the human P1/eIF-2 alpha protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNA

28 November 2018

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Functional expression and characterization of the interferon-induced double-stranded RNA activated P68 protein kinase from Escherichia coli

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Inhibitor of Interferon-Induced Double-Stranded RNA- Dependent Protein Kinase and Its Relevance to Alteration of Cellular Protein Kinase Activity Level in Response to External Stimuli

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Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI

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The double-stranded RNA-dependent protein kinase is also activated by heparin

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Autophosphorylation of the protein kinase dependent on double-stranded RNA

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2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expression

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Secreted placental alkaline phosphatase: a powerful new quantitative indicator of gene expression in eukaryotic cells

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