Mapping a gene involved in regulating dietary cholesterol absorption. The sitosterolemia locus is found at chromosome 2p21 (Q24564538)

2

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H Hidaka

3

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P O Kwiterovich

4

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A F Stalenhoef

5

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T A Miettinen

6

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S M Grundy

7

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M H Lee

8

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J S Rubenstein

9

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M H Polymeropoulos

10

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M J Brownstein

Journal of Clinical Investigation

11

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language of work or name

English

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publication date

1 September 1998

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published in

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volume

102

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page(s)

1041-4

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issue

5

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Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis

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Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function

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Increased plasma plant sterol levels in heterozygotes with sitosterolemia and xanthomatosis

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Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis

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The effect of increased hepatic sitosterol on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and cholesterol 7 alpha-hydroxylase in the rat and sitosterolemic homozygotes

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beta-Sitosterolemia with generalized eruptive xanthomatosis

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12 December 2020