Identification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gamma (Q24567657)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

review article

1 reference

title

Identification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gamma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

0 references

0 references

Eva-Maria Pferschy-Wenzig

1

1 reference

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9 March 2020

Atanas G. Atanasov

2

1 reference

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9 March 2020

Olaf Kunert

5

1 reference

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9 March 2020

Daniela Schuster

6

1 reference

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9 March 2020

Elke Heiss

7

1 reference

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9 March 2020

Nicholas H. Oberlies

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Rudolf Bauer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

Verena Dirsch

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

3

Clemens Malainer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

4

Stefan M Noha

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

author name string

Hildebert Wagner

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

language of work or name

English

0 references

publication date

5 March 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

Journal of Natural Products

9 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

volume

77

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

page(s)

842-847

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

Honokiol: a non-adipogenic PPARγ agonist from nature

9 March 2020

cites work

1 reference

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Polyacetylenes from Notopterygium incisum--new selective partial agonists of peroxisome proliferator-activated receptor-gamma

24 March 2017

1 reference

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Identification of hepatoprotective flavonolignans from silymarin

24 March 2017

1 reference

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Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma

24 March 2017

1 reference

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24 March 2017

The Protein Data Bank

1 reference

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Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

24 March 2017

1 reference

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Amorfrutins are potent antidiabetic dietary natural products

24 March 2017

1 reference

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Molecular Determinants of Magnolol Targeting Both RXRα and PPARγ

24 March 2017

1 reference

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A new technique for the assay of infectivity of human adenovirus 5 DNA

24 March 2017

1 reference

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Fibrates, glitazones, and peroxisome proliferator-activated receptors

24 March 2017

1 reference

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Safety issues and prospects for future generations of PPAR modulators

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Systematic review of herbs and dietary supplements for glycemic control in diabetes

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Natural products as sources of new drugs over the 30 years from 1981 to 2010

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

PPARs and the complex journey to obesity

7 April 2017

1 reference

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

PPARγ signaling and metabolism: the good, the bad and the future

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Nonalcoholic fatty liver disease: current issues and novel treatment approaches

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Modulation of PPAR-γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases

27 September 2017

1 reference

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Diabetes and nonalcoholic Fatty liver disease: a pathogenic duo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Natural cures for type 1 diabetes: a review of phytochemicals, biological actions, and clinical potential

27 September 2017

1 reference

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Nutraceuticals as Ligands of PPARγ

27 September 2017

1 reference

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Balaglitazone: a second generation peroxisome proliferator-activated receptor (PPAR) gamma (γ) agonist

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

N-Acetylfarnesylcysteine is a novel class of peroxisome proliferator-activated receptor γ ligand with partial and full agonist activity in vitro and in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Lipid-sensing nuclear receptors in the pathophysiology and treatment of the metabolic syndrome.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Methodologies for investigating natural medicines for the treatment of nonalcoholic fatty liver disease (NAFLD).

27 September 2017

1 reference

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Silymarin in the prevention and treatment of liver diseases and primary liver cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

27 September 2017

1 reference

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Dietary modulation of peroxisome proliferator-activated receptor gamma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Advances in the use of milk thistle (Silybum marianum).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Peroxisome proliferator-activated receptor structures: ligand specificity, molecular switch and interactions with regulators.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Non-alcoholic fatty liver disease: further expression of the metabolic syndrome

27 September 2017

1 reference

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The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Transcriptional regulation of metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Molecular Structure and Stereochemistry of Silybin A, Silybin B, Isosilybin A, and Isosilybin B, Isolated from Silybum marianum (Milk Thistle)

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

The use of silymarin in the treatment of liver diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Correlation between performance of QM/MM docking and simple classification of binding sites

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Gram-Scale Purification of Flavonolignan Diastereoisomers from Silybum marianum (Milk Thistle) Extract in Support of Preclinical in vivo Studies for Prostate Cancer Chemoprevention

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Complete isolation and characterization of silybins and isosilybins from milk thistle (Silybum marianum).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003856

Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24597776

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Anti-oxidant therapy in non-alcoholic fatty liver disease: the role of silymarin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24597776

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Notizen: Silydianin und Silychristin, zwei isomere Silymarine aus Silybum marianum L. Gaertn. (Mariendistel) / Silydianin and Silychristin, two Isomeric Silymarins from Silybum marianum L. Gaertn. (milk thistle)

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1515/ZNB-1976-0630

Identifiers

DOI

10.1021/NP400943B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24597776%20AND%20SRC:MED&resulttype=core&format=json