Epigenetic effects of green tea polyphenols in cancer (Q24568216)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24283885%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Epigenetic effects of green tea polyphenols in cancer (English)

1 reference

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1 March 2020

1 reference

0 references

3

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1 March 2020

author name string

Susanne M Henning

series ordinal

1

1 reference

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1 March 2020

Piwen Wang

series ordinal

2

1 reference

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1 March 2020

David Heber

series ordinal

4

1 reference

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1 March 2020

language of work or name

English

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publication date

1 December 2013

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1 March 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24283885%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

5

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1 March 2020

issue

6

1 reference

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1 March 2020

page(s)

729-741

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A decade of exploring the cancer epigenome - biological and translational implications

1 March 2020

cites work

1 reference

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Establishing, maintaining and modifying DNA methylation patterns in plants and animals

24 March 2017

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EUKARYOTIC CYTOSINE METHYLTRANSFERASES

24 March 2017

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DNA methylation patterns and epigenetic memory

24 March 2017

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Dietary factors and epigenetic regulation for prostate cancer prevention

24 March 2017

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Epigenetic diet: impact on the epigenome and cancer

24 March 2017

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Epigallocatechin gallate up-regulation of miR-16 and induction of apoptosis in human cancer cells

24 March 2017

1 reference

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Dietary polyphenols may affect DNA methylation

24 March 2017

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Mammalian DNA methyltransferases

24 March 2017

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Cancer epigenetics: from mechanism to therapy

24 March 2017

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DNA methylation landscapes: provocative insights from epigenomics

7 April 2017

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Phenotypic plasticity and the epigenetics of human disease

7 April 2017

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The epigenetic progenitor origin of human cancer

7 April 2017

1 reference

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DNA methylation and cancer development: molecular mechanism

7 April 2017

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MicroRNAs: an emerging science in cancer epigenetics

27 September 2017

1 reference

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Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.

27 September 2017

1 reference

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Phenolic acid concentrations in plasma and urine from men consuming green or black tea and potential chemopreventive properties for colon cancer

27 September 2017

1 reference

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Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms

27 September 2017

1 reference

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Reactivation of the tumour suppressor RASSF1A in breast cancer by simultaneous targeting of DNA and E2F1 methylation.

27 September 2017

1 reference

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Cancer chemoprevention with green tea catechins: from bench to bed.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

DNA methylation biomarkers and their utility for solid cancer diagnostics

27 September 2017

1 reference

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DNA methylation inhibitors in cancer: recent and future approaches

27 September 2017

1 reference

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Histone modifications and cancer: biomarkers of prognosis?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Cancer chemoprevention and nutriepigenetics: state of the art and future challenges

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Environmental exposures, epigenetics and cardiovascular disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Epigenetic inactivation of DNA repair in breast cancer.

27 September 2017

1 reference

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Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Epigenetic mechanisms in anti-cancer actions of bioactive food components--the implications in cancer prevention

27 September 2017

1 reference

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Quercetin increased bioavailability and decreased methylation of green tea polyphenols in vitro and in vivo

27 September 2017

1 reference

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Epigenetics and diabetes treatment: an unrealized promise?

27 September 2017

1 reference

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Polyphenols in brewed green tea inhibit prostate tumor xenograft growth by localizing to the tumor and decreasing oxidative stress and angiogenesis

27 September 2017

1 reference

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Dietary and lifestyle factors of DNA methylation

27 September 2017

1 reference

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Epigenetic programming of neurodegenerative diseases by an adverse environment

27 September 2017

1 reference

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Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

MicroRNAs in the pathogenesis of cancer

27 September 2017

1 reference

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Nutritional influences on epigenetics and age-related disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Epigenetic alterations in ultraviolet radiation-induced skin carcinogenesis: interaction of bioactive dietary components on epigenetic targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Induction of regulatory T cells by green tea polyphenol EGCG.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Mechanistic issues concerning cancer prevention by tea catechins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Chemopreventive effects of tea in prostate cancer: green tea versus black tea.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

A novel prodrug of epigallocatechin-3-gallate: differential epigenetic hTERT repression in human breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Cancer prevention by tea: Evidence from laboratory studies

27 September 2017

1 reference

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The chemistry and biotransformation of tea constituents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Comparison of a pair of synthetic tea-catechin-derived epimers: synthesis, antifolate activity, and tyrosinase-mediated activation in melanoma.

27 September 2017

1 reference

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Methylation of DNA in cancer

27 September 2017

1 reference

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Epigenetic targets of bioactive dietary components for cancer prevention and therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

27 September 2017

1 reference

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Epigenetics and maternal nutrition: nature v. nurture

27 September 2017

1 reference

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Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells

27 September 2017

1 reference

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Regulation of Nrf2- and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate cancer cells

27 September 2017

1 reference

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Nature or nurture: let food be your epigenetic medicine in chronic inflammatory disorders.

27 September 2017

1 reference

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Green tea polyphenols and metabolites in prostatectomy tissue: implications for cancer prevention

27 September 2017

1 reference

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Cancer chemoprevention by dietary polyphenols: promising role for epigenetics

27 September 2017

1 reference

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Tea catechin auto-oxidation dimers are accumulated and retained by Caco-2 human intestinal cells

27 September 2017

1 reference

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Epigenetics in atherosclerosis and inflammation

27 September 2017

1 reference

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Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells

27 September 2017

1 reference

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Rethinking how DNA methylation patterns are maintained

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Promoter demethylation of WIF-1 by epigallocatechin-3-gallate in lung cancer cells.

27 September 2017

1 reference

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Green tea and prostate cancer: from bench to clinic

27 September 2017

1 reference

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A thought on the biological activities of black tea.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Effective prostate cancer chemopreventive intervention with green tea polyphenols in the TRAMP model depends on the stage of the disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Epigallocatechin-3-gallate, a histone acetyltransferase inhibitor, inhibits EBV-induced B lymphocyte transformation via suppression of RelA acetylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Regulation of human dihydrofolate reductase activity and expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Nongallated compared with gallated flavan-3-ols in green and black tea are more bioavailable

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Biotransformation of green tea polyphenols and the biological activities of those metabolites

27 September 2017

1 reference

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Epigenetics and complex disease: from etiology to new therapeutics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Metabolism of dietary polyphenols and possible interactions with drugs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

A novel prodrug of the green tea polyphenol (-)-epigallocatechin-3-gallate as a potential anticancer agent

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Peracetylation as a means of enhancing in vitro bioactivity and bioavailability of epigallocatechin-3-gallate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Mechanisms for the inhibition of DNA methyltransferases by tea catechins and bioflavonoids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Bioavailability and antioxidant activity of tea flavanols after consumption of green tea, black tea, or a green tea extract supplement.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Exceptionally high protection of photocarcinogenesis by topical application of (--)-epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

An evaluation of new criteria for CpG islands in the human genome as gene markers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Effect of black and green tea polyphenols on c-jun phosphorylation and H(2)O(2) production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Mechanisms for epigallocatechin gallate induced inhibition of drug metabolizing enzymes in rat liver microsomes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Plasma pharmacokinetics of catechin metabolite 4'-O-Me-EGC in healthy humans

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Association of tissue promoter methylation levels of APC, TGFβ2, HOXD3 and RASSF1A with prostate cancer progression

30 May 2018

1 reference

Dose-response plasma appearance of green tea catechins in adults

21 January 2018

1 reference

Bioavailability of dietary (poly)phenols: a study with ileostomists to discriminate between absorption in small and large intestine

21 January 2018

1 reference

Identification and characterization of methylated and ring-fission metabolites of tea catechins formed in humans, mice, and rats

21 January 2018

1 reference

Absorption, metabolism and excretion of Choladi green tea flavan-3-ols by humans.

21 January 2018

1 reference

Methylation suppresses the proteasome-inhibitory function of green tea polyphenols

21 January 2018

1 reference

Inhibition of human liver catechol-O-methyltransferase by tea catechins and their metabolites: structure-activity relationship and molecular-modeling studies

21 January 2018

1 reference

Catechin degradation with concurrent formation of homo- and heterocatechin dimers during in vitro digestion

21 January 2018

1 reference

Pharmacokinetic and pharmacodynamic analysis of 5-aza-2'-deoxycytidine (decitabine) in the design of its dose-schedule for cancer therapy.

21 January 2018

1 reference

The antifolate activity of tea catechins.

21 January 2018

1 reference

Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer

21 January 2018

1 reference

Lack of evidence for green tea polyphenols as DNA methylation inhibitors in murine prostate

21 January 2018

1 reference

Epigallocatechin-3-Gallate suppresses early stage, but not late stage prostate cancer in TRAMP mice: mechanisms of action

21 January 2018

1 reference

Synergistic effects of a combination of dietary factors sulforaphane and (-) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells.

21 January 2018

1 reference

Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds

21 January 2018

1 reference

Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3970408

Prenatal tea consumption and risks of anencephaly and spina bifida

28 November 2018

1 reference

12 December 2020

Evaluation of global DNA hypomethylation in human prostate cancer and prostatic intraepithelial neoplasm tissues by immunohistochemistry

1 reference

12 December 2020

DNA methylation and cancer

1 reference

12 December 2020

Distribution of catechol-O-methyltransferase enzyme in rat tissues

1 reference

12 December 2020

Molecular modelling study of the mechanism of high-potency inhibition of human catechol-O-methyltransferase by (-)-epigallocatechin-3-O-gallate

1 reference

12 December 2020

Epigallocatechin-3-gallate is absorbed but extensively glucuronidated following oral administration to mice

1 reference

12 December 2020

Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women

1 reference

12 December 2020

Chemokines and B cells in renal inflammation and allograft rejection

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.2217/EPI.13.57

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24283885%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24283885%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

24283885

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24283885%20AND%20SRC:MED&resulttype=core&format=json