The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin (Q24594134)

2

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A Jacob Hassan

3

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Maryssa Canuel

4

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Carlos R Morales

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

5

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language of work or name

English

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publication date

15 December 2003

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published in

The EMBO Journal

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volume

22

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page(s)

6430-7

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issue

24

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cites work

1 reference

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A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome

24 March 2017

1 reference

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Crystal structure of plant aspartic proteinase prophytepsin: inactivation and vacuolar targeting

24 March 2017

1 reference

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Binding of GGA2 to the lysosomal enzyme sorting motif of the mannose 6-phosphate receptor

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Sorting of mannose 6-phosphate receptors mediated by the GGAs

24 March 2017

1 reference

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The GGAs promote ARF-dependent recruitment of clathrin to the TGN

24 March 2017

1 reference

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24 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

24 March 2017

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG629

Swaposins: circular permutations within genes encoding saposin homologues

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Assembly and function of AP-3 complexes in cells expressing mutant subunits.

24 March 2017

1 reference

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27 September 2017

Adaptor-related proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Identification of a novel sequence involved in lysosomal sorting of the sphingolipid activator protein prosaposin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Intracellular transport of GPI-anchored proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Role of sphingolipids in the transport of prosaposin to the lysosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Cellular uptake of saposin (SAP) precursor and lysosomal delivery by the low density lipoprotein receptor-related protein (LRP).

27 September 2017

1 reference

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Mouse testicular sulfated glycoprotein-1: sequence analysis of the common backbone structure of prosaposins.

27 September 2017

1 reference

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Two mechanisms for the recapture of extracellular GM2 activator protein: evidence for a major secretory form of the protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291824

Fibroblasts from patients with I-cell disease and pseudo-Hurler polydystrophy are deficient in uridine 5'-diphosphate-N-acetylglucosamine: glycoprotein N-acetylglucosaminylphosphotransferase activity.

27 September 2017

1 reference

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Structural requirements for intracellular transport of pulmonary surfactant protein B (SP-B).

27 September 2017

1 reference

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The lysosomal transport of prosaposin requires the conditional interaction of its highly conserved d domain with sphingomyelin

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG629

The mouse gene encoding the GM2 activator protein (Gm2a): cDNA sequence, expression, and chromosome mapping.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG629

Sphingolipid hydrolases and activator proteins

21 January 2018

1 reference

12 December 2020

Mutations in the cytoplasmic domain of the 275 kd mannose 6-phosphate receptor differentially alter lysosomal enzyme sorting and endocytosis

1 reference

12 December 2020

Mannose 6-phosphate-independent membrane association of cathepsin D, glucocerebrosidase, and sphingolipid-activating protein in HepG2 cells

1 reference

12 December 2020

Trafficking of sulfated glycoprotein-1 (prosaposin) to lysosomes or to the extracellular space in rat Sertoli cells

1 reference

12 December 2020

Biosynthesis, processing, and intracellular transport of GM2 activator protein in human epidermal keratinocytes. The lysosomal targeting of the GM2 activator is independent of a mannose-6-phosphate signal

1 reference

12 December 2020

Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): its mechanism and inhibition by ganglioside

1 reference

12 December 2020

Expression and characterization of saposin-like proteins

1 reference

12 December 2020

Lamellar body formation in normal and surfactant protein B-deficient fetal mice

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG629

1 reference

172073

172073

1 reference

1 reference

1 reference