Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy (Q24596354)

8

Kitt F Petersen

0 references

Gary W Cline

5

Gary W Cline

0 references

Douglas L Rothman

7

Douglas L Rothman

0 references

Graeme F Mason

2

Graeme F Mason

0 references

Fawzi Boumezbeur

1

Fawzi Boumezbeur

0 references

Kevin L Behar

4

Kevin L Behar

0 references

author name string

Robin A de Graaf

Journal of Cerebral Blood Flow & Metabolism

3

0 references

language of work or name

English

0 references

publication date

January 2010

0 references

published in

0 references

volume

30

0 references

page(s)

211-21

0 references

issue

1

0 references

cites work

Metabolic and hemodynamic events after changes in neuronal activity: current hypotheses, theoretical predictions and in vivo NMR experimental findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

N-acetylaspartate as a reservoir for glutamate

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Insights into the ageing mind: a view from cognitive neuroscience

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Mitochondrial dysfunction in the elderly: possible role in insulin resistance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

An energy budget for signaling in the grey matter of the brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Clinical NOE 13C MRS for neuropsychiatric disorders of the frontal lobe

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Determination of the glutamate-glutamine cycling flux using two-compartment dynamic metabolic modeling is sensitive to astroglial dilution

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

N-acetylaspartate and N-acetylaspartylglutamate: neurobiology and clinical significance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

MR spectroscopy in neurodegenerative disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Neuronal-glial glucose oxidation and glutamatergic-GABAergic function.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Magnetic resonance spectroscopy for studies of neurotransmission in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Structural changes that occur during normal aging of primate cerebral hemispheres

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Magnetic resonance spectroscopic approaches to studying neuronal: glial interactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Functional brain imaging in the resting state and during activation in Alzheimer's disease. Implications for disease mechanisms involving oxidative phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Regional cerebral glucose metabolism in late-life depression and Alzheimer disease: a preliminary positron emission tomography study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Quantitative proton spectroscopy of canine brain: in vivo and in vitro correlations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Changes in volume, surface estimate, three-dimensional shape and total number of neurons of the human primary visual cortex from midgestation until old age.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Toward dynamic isotopomer analysis in the rat brain in vivo: automatic quantitation of 13C NMR spectra using LCModel

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Diffuse cortical reduction of neuronal activity in unipolar major depression: a retrospective analysis of 337 patients and 321 controls

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Proton NMR chemical shifts and coupling constants for brain metabolites

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Decreases in regional cerebral blood flow with normal aging.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Morphometry of the human cortex cerebri and corpus striatum during aging.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

In vivo evidence for axonal dysfunction remote from focal cerebral demyelination of the type seen in multiple sclerosis.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Resting state brain glucose metabolism is not reduced in normotensive healthy men during aging, after correction for brain atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Human cerebral blood flow and oxygen consumption as related to aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Reduced glutamate neurotransmission in patients with Alzheimer's disease -- an in vivo (13)C magnetic resonance spectroscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Measurement of the tricarboxylic acid cycle rate in human grey and white matter in vivo by 1H-[13C] magnetic resonance spectroscopy at 4.1T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Graded image segmentation of brain tissue in the presence of inhomogeneous radio frequency fields.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Neuroglial metabolism in the awake rat brain: CO2 fixation increases with brain activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Histology and histochemistry of the aging cerebral cortex: an overview.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Thinning of the cerebral cortex in aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

On the reliability of (13)C metabolic modeling with two-compartment neuronal-glial models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2009.197

Longitudinal Magnetic Resonance Imaging Studies of Older Adults: A Shrinking Brain

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

A mathematical model of compartmentalized neurotransmitter metabolism in the human brain

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2949111

Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: effect of ageing

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19794401

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estimation of metabolite concentrations from localized in vivo proton NMR spectra

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19794401

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Analysis of macromolecule resonances in 1H NMR spectra of human brain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19794401

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/JCBFM.2009.197

1 reference

4720735

4720735

1 reference

1 reference

1 reference