Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases (Q24599204)

3

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Mark Livingstone

object named as

Mark Livingstone

4

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Franck Peiretti

object named as

Franck Peiretti

2

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author name string

Brian Raught

1

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David Shahbazian

5

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Greg L Mayeur

6

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Roberto D Polakiewicz

7

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John W B Hershey

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

9

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language of work or name

English

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publication date

21 April 2004

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published in

The EMBO Journal

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volume

23

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issue

8

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page(s)

1761-9

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cites work

1 reference

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A region rich in aspartic acid, arginine, tyrosine, and glycine (DRYG) mediates eukaryotic initiation factor 4B (eIF4B) self-association and interaction with eIF3

24 March 2017

1 reference

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The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequence

24 March 2017

1 reference

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An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

24 March 2017

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Cloning and expression of eukaryotic initiation factor 4B cDNA: sequence determination identifies a common RNA recognition motif

24 March 2017

1 reference

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The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

24 March 2017

1 reference

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The phosphoinositide 3-kinase pathway

24 March 2017

1 reference

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

24 March 2017

1 reference

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TOR, a central controller of cell growth

24 March 2017

1 reference

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TOR controls translation initiation and early G1 progression in yeast

24 March 2017

1 reference

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A Saccharomyces cerevisiae homologue of mammalian translation initiation factor 4B contributes to RNA helicase activity

24 March 2017

1 reference

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Two structural domains of initiation factor eIF-4B are involved in binding to RNA

24 March 2017

1 reference

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

24 March 2017

1 reference

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The mechanism of action of protein synthesis initiation factors from rabbit reticulocytes

24 March 2017

1 reference

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Initiation of mammalian protein synthesis. II. The assembly of the initiation complex with purified initiation factors

24 March 2017

1 reference

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

24 March 2017

1 reference

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Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

7 April 2017

1 reference

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Assembly of 48S translation initiation complexes from purified components with mRNAs that have some base pairing within their 5' untranslated regions.

7 April 2017

1 reference

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Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F.

27 September 2017

1 reference

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The target of rapamycin (TOR) proteins

27 September 2017

1 reference

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Regulation of cellular growth by the Drosophila target of rapamycin dTOR

27 September 2017

1 reference

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Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

27 September 2017

1 reference

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Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI.

27 September 2017

1 reference

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Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region

27 September 2017

1 reference

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Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

27 September 2017

1 reference

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Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Regulation of ornithine decarboxylase in a transformed cell line that overexpresses translation initiation factor eIF-4E.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Structural and functional analysis of pp70S6k

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Multiple independent inputs are required for activation of the p70 S6 kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Initiation factor protein modifications and inhibition of protein synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Identification and characterization of a mitogen-activated S6 kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

mRNAs containing extensive secondary structure in their 5' non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Translational control of protein synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Regulation of initiation factors during translational repression caused by serum depletion. Covalent modification

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Dissociation of double-stranded polynucleotide helical structures by eukaryotic initiation factors, as revealed by a novel assay

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Regulation of rat ornithine decarboxylase mRNA translation by its 5'-untranslated region

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Insulin induction of ornithine decarboxylase. Importance of mRNA secondary structure and phosphorylation of eucaryotic initiation factors eIF-4B and eIF-4E.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Quick guide: target of rapamycin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

28 November 2018

1 reference

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Orally administered leucine stimulates protein synthesis in skeletal muscle of postabsorptive rats in association with increased eIF4F formation.

28 November 2018

1 reference

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Drosophila S6 kinase: a regulator of cell size

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=394247

RNA-stimulated ATPase activity of eukaryotic initiation factors

28 November 2018

1 reference

12 December 2020

Biochemical and kinetic characterization of the RNA helicase activity of eukaryotic initiation factor 4A

1 reference

12 December 2020

Heat shock-induced translational alterations in HeLa cells. Initiation factor modifications and the inhibition of translation

1 reference

12 December 2020

Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600193

1 reference

1632865

1632865

1 reference

1 reference

1 reference