A new reagent for direct difluoromethylation (Q24599323)

2

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Rodrigo A Rodriguez

3

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Ryan D Baxter

4

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Darryl D Dixon

5

0 references

Michael R Collins

6

0 references

Donna G Blackmond

7

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Phil S Baran

Journal of the American Chemical Society

8

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language of work or name

English

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publication date

25 January 2012

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published in

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volume

134

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issue

3

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page(s)

1494-7

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cites work

Innate C-H trifluoromethylation of heterocycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

Innate and Guided C–H Functionalization Logic

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

Synthesis and biological evaluation of novel analogues of the pan class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474).

26 May 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

Synopsis of some recent tactical application of bioisosteres in drug design

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

Carbon-fluorine bond formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

Selective difluoromethylation and monofluoromethylation reactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269891

A new method for aromatic difluoromethylation: copper-catalyzed cross-coupling and decarboxylation sequence from aryl iodides

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22229949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Introduction: Fluorine Chemistry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22229949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/JA211422G

1 reference

release_jvjghnw4ovcjfoxcygc63t6kk4

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

22229949

1 reference