Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1 (Q24599839)

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3 February 2020

title

Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1 (English)

1 reference

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3 February 2020

0 references

3

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3 February 2020

author name string

Gary E Keck

1

1 reference

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3 February 2020

Yam B Poudel

2

1 reference

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3 February 2020

Jeffrey C Stephens

4

1 reference

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3 February 2020

Noemi Kedei

5

1 reference

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3 February 2020

Nancy E Lewin

6

1 reference

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3 February 2020

Megan L Peach

7

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3 February 2020

Peter M Blumberg

8

1 reference

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3 February 2020

language of work or name

English

0 references

publication date

1 June 2010

1 reference

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Angewandte Chemie International Edition

3 February 2020

published in

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3 February 2020

volume

49

1 reference

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3 February 2020

issue

27

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3 February 2020

page(s)

4580-4584

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Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches

3 February 2020

cites work

1 reference

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Bryostatin 1 induces prolonged activation of extracellular regulated protein kinases in and apoptosis of LNCaP human prostate cancer cells overexpressing protein kinase calpha

24 March 2017

1 reference

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Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester

24 March 2017

1 reference

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New approaches to the total synthesis of the bryostatin antitumor macrolides

24 March 2017

1 reference

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The bryostatin 1 A-ring acetate is not the critical determinant for antagonism of phorbol ester-induced biological responses

27 September 2017

1 reference

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Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester function

27 September 2017

1 reference

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Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy

27 September 2017

1 reference

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Synthetic Studies Toward Bryostatin 1: Preparation of a C(1)-C(16) Fragment by Pyran Annulation

27 September 2017

1 reference

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Protein kinase C and other diacylglycerol effectors in cancer

27 September 2017

1 reference

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Synthetic studies toward the bryostatins: a substrate-controlled approach to the A-ring

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

Synthetic studies on the bryostatins: preparation of a truncated BC-ring intermediate by pyran annulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

The practical synthesis of a novel and highly potent analogue of bryostatin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

The chemistry and biology of the bryostatin antitumour macrolides

27 September 2017

1 reference

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Protein kinase C isozymes and the regulation of diverse cell responses

27 September 2017

1 reference

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Total Synthesis of Bryostatin 3

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

Divergent effects of bryostatin 1 and phorbol myristate acetate on cell cycle arrest and maturation in human myelomonocytic leukemia cells (U937).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

Olefin metathesis involving ruthenium enoic carbene complexes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269168

Enantioselective formal total synthesis of the antitumor macrolide bryostatin 7

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20491108

12 December 2020

inferred from PubMed ID database lookup

The large-scale isolation of bryostatin 1 from Bugula neritina following current good manufacturing practices

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20491108

12 December 2020

inferred from PubMed ID database lookup

Synthesis of bryostatin 7

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANIE.201001200

7 January 2021

inferred from DOI database lookup

Isolation and structure of bryostatin 1

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANIE.201001200

7 January 2021

inferred from DOI database lookup

Total Synthesis of Bryostatin 2

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANIE.201001200

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1002/ANIE.201001200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20491108%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20491108%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference