A new generation of human artificial chromosomes for functional genomics and gene therapy (Q24599954)

2

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author name string

Natalay Kouprina

1

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Hiroshi Masumoto

3

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Vladimir Larionov

Cellular and Molecular Life Sciences

4

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language of work or name

English

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publication date

April 2013

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published in

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volume

70

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issue

7

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page(s)

1135-48

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cites work

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Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly

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27 September 2017

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Retroviral vectors for gene therapy

27 September 2017

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Destabilizing aneuploidy by targeting cell cycle and mitotic checkpoint proteins in cancer cells

27 September 2017

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Human artificial chromosome with a conditional centromere for gene delivery and gene expression.

27 September 2017

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Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer

27 September 2017

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Escherichia coli-cloned CFTR loci relevant for human artificial chromosome therapy.

27 September 2017

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Development of evaluation system for bioactive substances using human artificial chromosome-mediated osteocalcin gene expression

27 September 2017

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Recent advances in lentiviral vector development and applications

27 September 2017

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Cell to cell transfer of the chromatin-packaged human beta-globin gene cluster

27 September 2017

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Complete genetic correction of ips cells from Duchenne muscular dystrophy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Integrase-defective lentiviral vectors: progress and applications.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

A gene delivery system with a human artificial chromosome vector based on migration of mesenchymal stem cells towards human glioblastoma HTB14 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Integration-deficient lentiviral vectors: a slow coming of age.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Progress and prospects: biological properties and technological advances of herpes simplex virus type 1-based amplicon vectors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

HAC stability in murine cells is influenced by nuclear localization and chromatin organization

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Inactivation of a human kinetochore by specific targeting of chromatin modifiers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Introduction of a CD40L genomic fragment via a human artificial chromosome vector permits cell-type-specific gene expression and induces immunoglobulin secretion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Transfer of human artificial chromosome vectors into stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Human artificial chromosome vectors meet stem cells: new prospects for gene delivery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advances

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Human artificial chromosomes: potential applications and clinical considerations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

TAR cloning: insights into gene function, long-range haplotypes and genome structure and evolution

27 September 2017

1 reference

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A novel human artificial chromosome gene expression system using herpes simplex virus type 1 vectors.

27 September 2017

1 reference

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Human artificial chromosomes constructed using the bottom-up strategy are stably maintained in mitosis and efficiently transmissible to progeny mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Delivery of large genomic DNA inserts >100 kb using HSV-1 amplicons.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Progress in artificial chromosome technology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Engineered human dicentric chromosomes show centromere plasticity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression in human mesenchymal stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Construction of human artificial chromosome vectors by recombineering.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Construction of a novel human artificial chromosome vector for gene delivery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Human artificial chromosomes containing chromosome 17 alphoid DNA maintain an active centromere in murine cells but are not stable

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Human Artificial Chromosomes with Alpha Satellite-Based De Novo Centromeres Show Increased Frequency of Nondisjunction and Anaphase Lag

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Efficiency of de novo centromere formation in human artificial chromosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Strategies for engineering human chromosomes with therapeutic potential

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Efficient in-vitro transfer of a 60-Mb mammalian artificial chromosome into murine and hamster cells using cationic lipids and dendrimers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Stable gene expression from a mammalian artificial chromosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Functional complementation of a genetic deficiency with human artificial chromosomes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Human mini-chromosomes with minimal centromeres

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

A structurally defined mini-chromosome vector for the mouse germ line.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Use of a human minichromosome as a cloning and expression vector for mammalian cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Generation of an approximately 2.4 Mb human X centromere-based minichromosome by targeted telomere-associated chromosome fragmentation in DT40.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Construction of YAC-based mammalian artificial chromosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Mini-chromosomes derived from the human Y chromosome by telomere directed chromosome breakage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Specific cloning of human DNA as yeast artificial chromosomes by transformation-associated recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Microcell-mediated transfer of murine chromosomes into mouse, Chinese hamster, and human somatic cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Generation of pluripotent stem cells from neonatal mouse testis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Controlled transgene dosage and PAC-mediated transgenesis in mice using a chromosomal vector.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Functional human CFTR produced by a stable minichromosome

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Construction of mouse A9 clones containing a single human chromosome tagged with neomycin-resistance gene via microcell fusion

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Telomere-associated chromosome fragmentation: applications in genome manipulation and analysis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522797

Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes

30 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Construction and use of a bottom-up HAC vector for transgene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Dissecting the centromere of the human Y chromosome with cloned telomeric DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Input DNA ratio determines copy number of the 33 kb Factor IX gene on de novo human artificial chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Antigen-specific human polyclonal antibodies from hyperimmunized cattle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Treatment of nonalbumin rats by transplantation of immortalized hepatocytes using artificial human chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

A novel expression system for genomic DNA loci using a human artificial chromosome vector with transformation-associated recombination cloning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1113-3

Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

12 December 2020

Mammalian artificial chromosome formation from circular alphoid input DNA does not require telomere repeats

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12 December 2020

Cloned transchromosomic calves producing human immunoglobulin

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12 December 2020

Murine leukemia induced by retroviral gene marking

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12 December 2020

10.1007/S00018-012-1113-3

Identifiers

DOI

1 reference

Dimensions Publication ID

582450

1006963922

0 references

582450

1 reference

1 reference

1 reference