Second sialic acid binding site in Newcastle disease virus hemagglutinin-neuraminidase: implications for fusion (Q24600140)

20 October 2023

Viatcheslav Zaitsev

1

Viatcheslav

Zaitsev

1 reference

20 October 2023

Mark von Itzstein

2

Mark

von Itzstein

1 reference

20 October 2023

Darrin Groves

3

Darrin

Groves

1 reference

20 October 2023

Milton Kiefel

4

Milton

Kiefel

1 reference

20 October 2023

Toru Takimoto

5

Toru

Takimoto

1 reference

20 October 2023

Garry Taylor

7

Garry

Taylor

1 reference

Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxovirus-cell membrane fusion

20 October 2023

language of work or name

English

0 references

publication date

April 2004

0 references

published in

Journal of Virology

0 references

volume

78

0 references

issue

7

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page(s)

3733-41

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cites work

1 reference

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7 April 2017

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The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusion

7 April 2017

1 reference

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Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase

7 April 2017

1 reference

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Structural basis for paramyxovirus-mediated membrane fusion

7 April 2017

1 reference

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Structural evidence for a second sialic acid binding site in avian influenza virus neuraminidases

7 April 2017

1 reference

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Structure of influenza haemagglutinin at the pH of membrane fusion

7 April 2017

1 reference

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Influenza B virus neuraminidase can synthesize its own inhibitor

7 April 2017

1 reference

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The structure of the complex between influenza virus neuraminidase and sialic acid, the viral receptor

7 April 2017

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7 April 2017

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7 April 2017

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

7 April 2017

1 reference

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

7 April 2017

1 reference

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The structural biology of type I viral membrane fusion

7 April 2017

1 reference

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Interacting Domains of the HN and F Proteins of Newcastle Disease Virus

7 April 2017

1 reference

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Fusion deficiency induced by mutations at the dimer interface in the Newcastle disease virus hemagglutinin-neuraminidase is due to a temperature-dependent defect in receptor binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Probing the sialic acid binding site of the hemagglutinin-neuraminidase of Newcastle disease virus: identification of key amino acids involved in cell binding, catalysis, and fusion.

27 September 2017

1 reference

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Structural and functional relationship between the receptor recognition and neuraminidase activities of the Newcastle disease virus hemagglutinin-neuraminidase protein: receptor recognition is dependent on neuraminidase activity

27 September 2017

1 reference

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Crystallization of Newcastle disease virus hemagglutinin-neuraminidase glycoprotein

27 September 2017

1 reference

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Amino acid substitutions in a conserved region in the stalk of the Newcastle disease virus HN glycoprotein spike impair its neuraminidase activity in the globular domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Mutations in the Newcastle disease virus hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusion

27 September 2017

1 reference

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Functional interaction of paramyxovirus glycoproteins: identification of a domain in Sendai virus HN which promotes cell fusion

27 September 2017

1 reference

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Paramyxovirus fusion: a hypothesis for changes

27 September 2017

1 reference

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Site-directed mutagenesis of a conserved hexapeptide in the paramyxovirus hemagglutinin-neuraminidase glycoprotein: effects on antigenic structure and function

27 September 2017

1 reference

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Protein-protein interactions within paramyxoviruses identified by native disulfide bonding or reversible chemical cross-linking

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Structure, function, and intracellular processing of paramyxovirus membrane proteins

27 September 2017

1 reference

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Isolation of a biologically active soluble form of the hemagglutinin-neuraminidase protein of Sendai virus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Topological and operational delineation of antigenic sites on the HN glycoprotein of Newcastle disease virus and their structural requirements

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Neutralization map of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus: domains recognized by monoclonal antibodies that prevent receptor recognition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Evidence for a sialosyl cation transition-state complex in the reaction of sialidase from influenza virus

27 September 2017

1 reference

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Fusion mutants of Newcastle disease virus selected with monoclonal antibodies to the hemagglutinin-neuraminidase

27 September 2017

1 reference

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Functional interactions between the fusion protein and hemagglutinin-neuraminidase of human parainfluenza viruses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Sialidases: structures, biological significance and therapeutic potential

27 September 2017

1 reference

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A single amino acid changes enhances the fusion promotion activity of human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoprotein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

The attachment function of the Newcastle disease virus hemagglutinin-neuraminidase protein can be separated from fusion promotion by mutation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Monoclonal antibodies as functional probes of the HN glycoprotein of Newcastle disease virus: antigenic separation of the hemagglutinating and neuraminidase sites

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Localization of functional sites on the hemagglutinin-neuraminidase glycoprotein of Sendai virus by sequence analysis of antigenic and temperature-sensitive mutants

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Identification of amino acid residues important to the neuraminidase activity of the HN glycoprotein of Newcastle disease virus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Functional and neutralization profile of seven overlapping antigenic sites on the HN glycoprotein of Newcastle disease virus: monoclonal antibodies to some sites prevent viral attachment

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Mapping of three antigenic sites on the haemagglutinin-neuraminidase protein of Newcastle disease virus

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

A single amino acid substitution in the hemagglutinin-neuraminidase of Newcastle disease virus results in a protein deficient in both functions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Modulation of the neuraminidase activity of HN protein from Newcastle disease virus by substrate binding and conformational change: kinetic and thermal denaturation studies.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Regions on the hemagglutinin-neuraminidase proteins of human parainfluenza virus type-1 and Sendai virus important for membrane fusion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Identification of regions on the hemagglutinin-neuraminidase protein of human parainfluenza virus type 2 important for promoting cell fusion

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Distinct functions of antigenic sites of the HN glycoprotein of Sendai virus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=371092

Inhibition of the neuraminidase of paramyxoviruses by halide ions: A possible means of modulating the two activities of the HN protein

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15016893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cooperative neuraminidase activity in a paramyxovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15016893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.78.7.3733-3741.2004

1 reference

1 reference

1 reference

1 reference